Novel chiral di-2-pyridyl ketone ligands: Crystal structure of a copper complex and its activity in the copper-catalyzed enantioselective cyclopropanation of styrene

Hoi Lun Kwong, Leung Shi Cheng, Wing Sze Lee, Wing Leung Wong, Wing Tak Wong

Research output: Journal article publicationJournal articleAcademic researchpeer-review

20 Citations (Scopus)

Abstract

New C2-symmetric chiral di-2-pyridyl ketones were prepared from readily available chiral bromopyridines. Their complexes with copper were synthesized and characterized by X-ray crystallography. The copper complexes were prepared in situ with the triflate anion and were found to be active in the catalysis of cyclopropanation with diazo esters and alkenes. Reaction yields were excellent and enantioselectivities of up to 61% were observed.
Original languageEnglish
Pages (from-to)1997-2002
Number of pages6
JournalEuropean Journal of Inorganic Chemistry
Issue number9
Publication statusPublished - 1 Jan 2000
Externally publishedYes

Keywords

  • Asymmetric catalysis
  • Chiral auxiliaries
  • Copper
  • Cyclopropanation
  • Nitrogen heterocycles
  • Pyridyl

ASJC Scopus subject areas

  • Inorganic Chemistry

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