Novel chiral di-2-pyridyl ketone ligands: Crystal structure of a copper complex and its activity in the copper-catalyzed enantioselective cyclopropanation of styrene

Hoi Lun Kwong; Leung Shi Cheng; Wing Sze Lee; Wing Leung Wong; Wing Tak Wong

Novel chiral di-2-pyridyl ketone ligands: Crystal structure of a copper complex and its activity in the copper-catalyzed enantioselective cyclopropanation of styrene

Hoi Lun Kwong, Leung Shi Cheng, Wing Sze Lee, Wing Leung Wong, Wing Tak Wong

Research output: Journal article publication › Journal article › Academic research › peer-review

Abstract

New C2-symmetric chiral di-2-pyridyl ketones were prepared from readily available chiral bromopyridines. Their complexes with copper were synthesized and characterized by X-ray crystallography. The copper complexes were prepared in situ with the triflate anion and were found to be active in the catalysis of cyclopropanation with diazo esters and alkenes. Reaction yields were excellent and enantioselectivities of up to 61% were observed.

Original language	English
Pages (from-to)	1997-2002
Number of pages	6
Journal	European Journal of Inorganic Chemistry
Issue number	9
Publication status	Published - 1 Jan 2000
Externally published	Yes

Keywords

Asymmetric catalysis
Chiral auxiliaries
Copper
Cyclopropanation
Nitrogen heterocycles
Pyridyl

ASJC Scopus subject areas

Inorganic Chemistry

Cite this

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title = "Novel chiral di-2-pyridyl ketone ligands: Crystal structure of a copper complex and its activity in the copper-catalyzed enantioselective cyclopropanation of styrene",

abstract = "New C2-symmetric chiral di-2-pyridyl ketones were prepared from readily available chiral bromopyridines. Their complexes with copper were synthesized and characterized by X-ray crystallography. The copper complexes were prepared in situ with the triflate anion and were found to be active in the catalysis of cyclopropanation with diazo esters and alkenes. Reaction yields were excellent and enantioselectivities of up to 61% were observed.",

keywords = "Asymmetric catalysis, Chiral auxiliaries, Copper, Cyclopropanation, Nitrogen heterocycles, Pyridyl",

author = "Kwong, {Hoi Lun} and Cheng, {Leung Shi} and Lee, {Wing Sze} and Wong, {Wing Leung} and Wong, {Wing Tak}",

year = "2000",

month = jan,

day = "1",

language = "English",

pages = "1997--2002",

journal = "European Journal of Inorganic Chemistry",

issn = "1434-1948",

publisher = "Wiley-VCH Verlag",

number = "9",

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Novel chiral di-2-pyridyl ketone ligands: Crystal structure of a copper complex and its activity in the copper-catalyzed enantioselective cyclopropanation of styrene. / Kwong, Hoi Lun; Cheng, Leung Shi; Lee, Wing Sze et al.
In: European Journal of Inorganic Chemistry, No. 9, 01.01.2000, p. 1997-2002.

Research output: Journal article publication › Journal article › Academic research › peer-review

TY - JOUR

T1 - Novel chiral di-2-pyridyl ketone ligands: Crystal structure of a copper complex and its activity in the copper-catalyzed enantioselective cyclopropanation of styrene

AU - Kwong, Hoi Lun

AU - Cheng, Leung Shi

AU - Lee, Wing Sze

AU - Wong, Wing Leung

AU - Wong, Wing Tak

PY - 2000/1/1

Y1 - 2000/1/1

N2 - New C2-symmetric chiral di-2-pyridyl ketones were prepared from readily available chiral bromopyridines. Their complexes with copper were synthesized and characterized by X-ray crystallography. The copper complexes were prepared in situ with the triflate anion and were found to be active in the catalysis of cyclopropanation with diazo esters and alkenes. Reaction yields were excellent and enantioselectivities of up to 61% were observed.

AB - New C2-symmetric chiral di-2-pyridyl ketones were prepared from readily available chiral bromopyridines. Their complexes with copper were synthesized and characterized by X-ray crystallography. The copper complexes were prepared in situ with the triflate anion and were found to be active in the catalysis of cyclopropanation with diazo esters and alkenes. Reaction yields were excellent and enantioselectivities of up to 61% were observed.

KW - Asymmetric catalysis

KW - Chiral auxiliaries

KW - Copper

KW - Cyclopropanation

KW - Nitrogen heterocycles

KW - Pyridyl

UR - http://www.scopus.com/inward/record.url?scp=0033802421&partnerID=8YFLogxK

M3 - Journal article

SN - 1434-1948

SP - 1997

EP - 2002

JO - European Journal of Inorganic Chemistry

JF - European Journal of Inorganic Chemistry

IS - 9

ER -

Novel chiral di-2-pyridyl ketone ligands: Crystal structure of a copper complex and its activity in the copper-catalyzed enantioselective cyclopropanation of styrene

Abstract

Keywords

ASJC Scopus subject areas

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