Novel adaptive control system for ultrasound hyperthermia treatment of prostate disease

Lei Sun, J. Schiano, N. B. Smith

Research output: Journal article publicationConference articleAcademic researchpeer-review

4 Citations (Scopus)


A novel model reference adaptive control (MRAC) method was proposed and tested with a transrectal intracavitary applicator for thermal treatment of prostate disease using ultrasound hyperthermia. Two significant advantages of this innovative adaptive control method are: 1) there is no need of a priori knowledge of the tissue properties and 2) the controller could adaptively change the amplitudes and phases of the array's driving signal according to the perfusion rate and other dynamic tissue properties. Computer simulations, ex vivo and in vivo experimental results all showed that with this adaptive controller the tissue was heated up to 43 ± 0.2°C within 7 ± 2 minutes, and adaptively maintained 43°C with dynamic blood flow for the rest period of the hyperthermia.
Original languageEnglish
Pages (from-to)1274-1277
Number of pages4
JournalProceedings of the IEEE Ultrasonics Symposium
Publication statusPublished - 1 Dec 2003
Externally publishedYes
Event2003 IEEE Ultrasonics Symposium - Proceedings - Honolulu, HI, United States
Duration: 5 Oct 20038 Oct 2003

ASJC Scopus subject areas

  • General Engineering


Dive into the research topics of 'Novel adaptive control system for ultrasound hyperthermia treatment of prostate disease'. Together they form a unique fingerprint.

Cite this