Abstract
A novel model reference adaptive control (MRAC) method was proposed and tested with a transrectal intracavitary applicator for thermal treatment of prostate disease using ultrasound hyperthermia. Two significant advantages of this innovative adaptive control method are: 1) there is no need of a priori knowledge of the tissue properties and 2) the controller could adaptively change the amplitudes and phases of the array's driving signal according to the perfusion rate and other dynamic tissue properties. Computer simulations, ex vivo and in vivo experimental results all showed that with this adaptive controller the tissue was heated up to 43 ± 0.2°C within 7 ± 2 minutes, and adaptively maintained 43°C with dynamic blood flow for the rest period of the hyperthermia.
Original language | English |
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Pages (from-to) | 1274-1277 |
Number of pages | 4 |
Journal | Proceedings of the IEEE Ultrasonics Symposium |
Volume | 2 |
Publication status | Published - 1 Dec 2003 |
Externally published | Yes |
Event | 2003 IEEE Ultrasonics Symposium - Proceedings - Honolulu, HI, United States Duration: 5 Oct 2003 → 8 Oct 2003 |
ASJC Scopus subject areas
- General Engineering