Nonwoven supported temperature-sensitive poly(N-isopropylacrylamide)/ polyurethane copolymer hydrogel with antibacterial aetivity

Baohua Liu, Jinlian Hu, Qinghao Meng

Research output: Journal article publicationJournal articleAcademic researchpeer-review

58 Citations (Scopus)


This article is focused on the study of the antibacterial activity of temperature sensitive poly(N-isopropylacrylainide/polyurethane (PNIPAAm/PU) hydrogel grafted non-woven fabrics with chitosan modification, A series of temperature sensitive hydrogel grafted nonwoven fabrics with different N-isopropylacrylamide/polyurethane (NIPAAm/PU) feeding ratios have been synthesized by using ammonium persulfate (APS) as initiator and N,N,N′,N′-tetramethyl-ethane-l,2-diamine (TEMED) as accelerator. FTIR and XPS were used to examine the surface modification of chitosan. The phase transition temperature of hydrogel grafted nonwoven fabrics was about 32°C by DSC. S. aureus and E. cott were used to evaluate the antibacterial efficiency of the fabric composite. After chitosan modification, the hydrogel grafted nonwoven cellulose fabrics demonstrates an antibacterial activity to S. aureus. and E, coll and the antibacterial efficiency is about 80%.
Original languageEnglish
Pages (from-to)1-8
Number of pages8
JournalJournal of Biomedical Materials Research - Part B Applied Biomaterials
Issue number1
Publication statusPublished - 1 Apr 2009


  • Antimicrobial
  • Fiber
  • Hydrogel
  • Polyurethane(s)
  • Wound dressings

ASJC Scopus subject areas

  • Biomedical Engineering
  • Biomaterials
  • Medicine(all)

Cite this