Non-contact measurement of young's modulus of single living cell using hydrostatic pressure in a microchamber

L. A.G. Lin; Y. F. Yu; A. Q. Liu; P. H. Yap

Non-contact measurement of young's modulus of single living cell using hydrostatic pressure in a microchamber

L. A.G. Lin
, Y. F. Yu
, A. Q. Liu
, P. H. Yap

Research output: Chapter in book / Conference proceeding › Conference article published in proceeding or book › Academic research › peer-review

3 Citations (Scopus)

Abstract

This paper introduces a biochip which contains a microchamber for measuring the mechanical properties of cells without physically touching them. Unlike previous methods, dissipative forces such as friction are avoidable increasing the accuracy of our measurements. This can be used for cancer detection at an early stage based on the fact that cancerous cells are more elastic than normal cells as well as for studying the effects of hydrostatic pressure on the biochemical pathways in the cell.

Original language	English
Title of host publication	Proceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007
Editors	Jean-Louis Viovy, Patrick Tabeling, Stephanie Descroix, Laurent Malaquin
Publisher	Chemical and Biological Microsystems Society
Pages	1354-1356
Number of pages	3
ISBN (Electronic)	9780979806407
Publication status	Published - Oct 2007
Externally published	Yes
Event	11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007 - Paris, France Duration: 7 Oct 2007 → 11 Oct 2007

Publication series

Name	Proceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007

Conference

Conference	11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007
Country/Territory	France
City	Paris
Period	7/10/07 → 11/10/07

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Biochip
Light scattering theory
Living cell
Young's modulus

ASJC Scopus subject areas

Chemical Engineering (miscellaneous)
Bioengineering

Cite this

Lin, L. A. G., Yu, Y. F., Liu, A. Q., & Yap, P. H. (2007). Non-contact measurement of young's modulus of single living cell using hydrostatic pressure in a microchamber. In J.-L. Viovy, P. Tabeling, S. Descroix, & L. Malaquin (Eds.), Proceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007 (pp. 1354-1356). (Proceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007). Chemical and Biological Microsystems Society.

Lin, L. A.G. ; Yu, Y. F. ; Liu, A. Q. et al. / Non-contact measurement of young's modulus of single living cell using hydrostatic pressure in a microchamber. Proceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007. editor / Jean-Louis Viovy ; Patrick Tabeling ; Stephanie Descroix ; Laurent Malaquin. Chemical and Biological Microsystems Society, 2007. pp. 1354-1356 (Proceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007).

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title = "Non-contact measurement of young's modulus of single living cell using hydrostatic pressure in a microchamber",

abstract = "This paper introduces a biochip which contains a microchamber for measuring the mechanical properties of cells without physically touching them. Unlike previous methods, dissipative forces such as friction are avoidable increasing the accuracy of our measurements. This can be used for cancer detection at an early stage based on the fact that cancerous cells are more elastic than normal cells as well as for studying the effects of hydrostatic pressure on the biochemical pathways in the cell.",

keywords = "Biochip, Light scattering theory, Living cell, Young's modulus",

author = "Lin, \{L. A.G.\} and Yu, \{Y. F.\} and Liu, \{A. Q.\} and Yap, \{P. H.\}",

note = "Publisher Copyright: {\textcopyright} 2007 CBMS.; 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007 ; Conference date: 07-10-2007 Through 11-10-2007",

year = "2007",

month = oct,

language = "English",

series = "Proceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007",

publisher = "Chemical and Biological Microsystems Society",

pages = "1354--1356",

editor = "Jean-Louis Viovy and Patrick Tabeling and Stephanie Descroix and Laurent Malaquin",

booktitle = "Proceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007",

}

Lin, LAG, Yu, YF, Liu, AQ & Yap, PH 2007, Non-contact measurement of young's modulus of single living cell using hydrostatic pressure in a microchamber. in J-L Viovy, P Tabeling, S Descroix & L Malaquin (eds), Proceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007. Proceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007, Chemical and Biological Microsystems Society, pp. 1354-1356, 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007, Paris, France, 7/10/07.

Non-contact measurement of young's modulus of single living cell using hydrostatic pressure in a microchamber. / Lin, L. A.G.; Yu, Y. F.; Liu, A. Q. et al.
Proceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007. ed. / Jean-Louis Viovy; Patrick Tabeling; Stephanie Descroix; Laurent Malaquin. Chemical and Biological Microsystems Society, 2007. p. 1354-1356 (Proceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007).

Research output: Chapter in book / Conference proceeding › Conference article published in proceeding or book › Academic research › peer-review

TY - GEN

T1 - Non-contact measurement of young's modulus of single living cell using hydrostatic pressure in a microchamber

AU - Lin, L. A.G.

AU - Yu, Y. F.

AU - Liu, A. Q.

AU - Yap, P. H.

PY - 2007/10

Y1 - 2007/10

N2 - This paper introduces a biochip which contains a microchamber for measuring the mechanical properties of cells without physically touching them. Unlike previous methods, dissipative forces such as friction are avoidable increasing the accuracy of our measurements. This can be used for cancer detection at an early stage based on the fact that cancerous cells are more elastic than normal cells as well as for studying the effects of hydrostatic pressure on the biochemical pathways in the cell.

AB - This paper introduces a biochip which contains a microchamber for measuring the mechanical properties of cells without physically touching them. Unlike previous methods, dissipative forces such as friction are avoidable increasing the accuracy of our measurements. This can be used for cancer detection at an early stage based on the fact that cancerous cells are more elastic than normal cells as well as for studying the effects of hydrostatic pressure on the biochemical pathways in the cell.

KW - Biochip

KW - Light scattering theory

KW - Living cell

KW - Young's modulus

UR - https://www.scopus.com/pages/publications/85017735629

M3 - Conference article published in proceeding or book

AN - SCOPUS:85017735629

T3 - Proceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007

SP - 1354

EP - 1356

BT - Proceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007

A2 - Viovy, Jean-Louis

A2 - Tabeling, Patrick

A2 - Descroix, Stephanie

A2 - Malaquin, Laurent

PB - Chemical and Biological Microsystems Society

T2 - 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007

Y2 - 7 October 2007 through 11 October 2007

ER -

Lin LAG, Yu YF, Liu AQ, Yap PH. Non-contact measurement of young's modulus of single living cell using hydrostatic pressure in a microchamber. In Viovy JL, Tabeling P, Descroix S, Malaquin L, editors, Proceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007. Chemical and Biological Microsystems Society. 2007. p. 1354-1356. (Proceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007).

Non-contact measurement of young's modulus of single living cell using hydrostatic pressure in a microchamber

Abstract

Publication series

Conference

UN SDGs

Keywords

ASJC Scopus subject areas

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