Non-contact measurement of young's modulus of single living cell using hydrostatic pressure in a microchamber

L. A.G. Lin, Y. F. Yu, A. Q. Liu, P. H. Yap

Research output: Chapter in book / Conference proceedingConference article published in proceeding or bookAcademic researchpeer-review

3 Citations (Scopus)

Abstract

This paper introduces a biochip which contains a microchamber for measuring the mechanical properties of cells without physically touching them. Unlike previous methods, dissipative forces such as friction are avoidable increasing the accuracy of our measurements. This can be used for cancer detection at an early stage based on the fact that cancerous cells are more elastic than normal cells as well as for studying the effects of hydrostatic pressure on the biochemical pathways in the cell.

Original languageEnglish
Title of host publicationProceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007
EditorsJean-Louis Viovy, Patrick Tabeling, Stephanie Descroix, Laurent Malaquin
PublisherChemical and Biological Microsystems Society
Pages1354-1356
Number of pages3
ISBN (Electronic)9780979806407
Publication statusPublished - Oct 2007
Externally publishedYes
Event11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007 - Paris, France
Duration: 7 Oct 200711 Oct 2007

Publication series

NameProceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007

Conference

Conference11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007
Country/TerritoryFrance
CityParis
Period7/10/0711/10/07

Keywords

  • Biochip
  • Light scattering theory
  • Living cell
  • Young's modulus

ASJC Scopus subject areas

  • Chemical Engineering (miscellaneous)
  • Bioengineering

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