Nickel-catalyzed asymmetric α-arylation of ketone enolates

Guoshu Chen, Fuk Yee Kwong, Hoi On Chan, Wing Yiu Yu, Albert S.C. Chan

Research output: Journal article publicationJournal articleAcademic researchpeer-review

105 Citations (Scopus)


An atropisomeric dipyridyldiphosphine, P-Phos, can effect highly enantioselective Ni-catalyzed α-arylation of ketone enolates with aryl halides to install an all-carbon quaternary stereogenic center in up to 98% ee and excellent yields.
Original languageEnglish
Pages (from-to)1413-1415
Number of pages3
JournalChemical Communications
Issue number13
Publication statusPublished - 24 Mar 2006

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry


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