New results on energy balance analysis of metabolic networks

Qinghua Zhou, Chi Keung Simon Shiu, Sankar K. Pal, Yan Li

Research output: Chapter in book / Conference proceedingConference article published in proceeding or bookAcademic researchpeer-review

Abstract

A central and long-standing objective of cellular physiology has been to understand the metabolic capabilities of living cells. In this paper, we perform optimization of metabolic networks in E.Coli under both flux and energy balance constraints. The impact of the energy balance is investigated on the behavior of metabolic networks. Different from the existing work, the preliminary results showed that the impact of imposing energy balance constraints on the biological metabolic systems is very limited.
Original languageEnglish
Title of host publicationPattern Recognition and Machine Intelligence - Second International Conference, PReMI 2007, Proceedings
Pages433-438
Number of pages6
Publication statusPublished - 1 Dec 2007
Event2nd International Conference on Pattern Recognition and Machine Intelligence, PReMI 2007 - Kolkata, India
Duration: 18 Dec 200722 Dec 2007

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume4815 LNCS
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349

Conference

Conference2nd International Conference on Pattern Recognition and Machine Intelligence, PReMI 2007
CountryIndia
CityKolkata
Period18/12/0722/12/07

Keywords

  • Constraint optimization
  • Energy balance analysis
  • Flux balance analysis
  • Metabolic networks

ASJC Scopus subject areas

  • Theoretical Computer Science
  • Computer Science(all)

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