TY - GEN
T1 - New results on energy balance analysis of metabolic networks
AU - Zhou, Qinghua
AU - Shiu, Chi Keung Simon
AU - Pal, Sankar K.
AU - Li, Yan
PY - 2007/12/1
Y1 - 2007/12/1
N2 - A central and long-standing objective of cellular physiology has been to understand the metabolic capabilities of living cells. In this paper, we perform optimization of metabolic networks in E.Coli under both flux and energy balance constraints. The impact of the energy balance is investigated on the behavior of metabolic networks. Different from the existing work, the preliminary results showed that the impact of imposing energy balance constraints on the biological metabolic systems is very limited.
AB - A central and long-standing objective of cellular physiology has been to understand the metabolic capabilities of living cells. In this paper, we perform optimization of metabolic networks in E.Coli under both flux and energy balance constraints. The impact of the energy balance is investigated on the behavior of metabolic networks. Different from the existing work, the preliminary results showed that the impact of imposing energy balance constraints on the biological metabolic systems is very limited.
KW - Constraint optimization
KW - Energy balance analysis
KW - Flux balance analysis
KW - Metabolic networks
UR - http://www.scopus.com/inward/record.url?scp=38149123336&partnerID=8YFLogxK
M3 - Conference article published in proceeding or book
SN - 3540770453
SN - 9783540770459
T3 - Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
SP - 433
EP - 438
BT - Pattern Recognition and Machine Intelligence - Second International Conference, PReMI 2007, Proceedings
T2 - 2nd International Conference on Pattern Recognition and Machine Intelligence, PReMI 2007
Y2 - 18 December 2007 through 22 December 2007
ER -