New perspectives on innovative drug discovery: An overview

Si Yuan Pan, Shan Pan, Zhi Ling Yu, Dik Lung Ma, Si Bao Chen, Wang Fun Fong, Yifan Han, Kam Ming Ko

Research output: Journal article publicationJournal articleAcademic researchpeer-review

31 Citations (Scopus)

Abstract

Despite advances in technology, drug discovery is still a lengthy, expensive, difficult, and inefficient process, with a low rate of success. Today, advances in biomedical science have brought about great strides in therapeutic interventions for a wide spectrum of diseases. The advent of biochemical techniques and cutting-edge bio/chemical technologies has made available a plethora of practical approaches to drug screening and design. In 2010, the total sales of the global pharmaceutical market will reach 600 billion US dollars and expand to over 975 billion dollars by 2013. The aim of this review is to summarize available information on contemporary approaches and strategies in the discovery of novel therapeutic agents, especially from the complementary and alternative medicines, including natural products and traditional remedies such as Chinese herbal medicine.
Original languageEnglish
Pages (from-to)450-471
Number of pages22
JournalJournal of Pharmacy and Pharmaceutical Sciences
Volume13
Issue number3
DOIs
Publication statusPublished - 1 Jan 2010

ASJC Scopus subject areas

  • Pharmacology
  • Pharmaceutical Science

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