Neurological Disorders

B. W. Man Lau, Suk Yu Yau, K. T. Po, K. F. So

Research output: Chapter in book / Conference proceedingChapter in an edited book (as author)Academic researchpeer-review

Abstract

The generation and functional integration of adult-born neurons in the hippocampus and subventricular zone suggest an important mechanism of neural plasticity in the adult brain. Dysregulation in adult neurogenesis has been commonly reported in several neurological disorders, suggesting its potential role in the development and pathology of the disorders. Adult neurogenesis might also be involved in the therapeutic process, thereby alleviating the neurological symptoms. We provide an overview of altered adult neurogenesis in animal models and human brains in neurodegenerative diseases, neurodevelopmental disorders, and brain injuries.
Original languageEnglish
Title of host publicationAdult Neurogenesis in the Hippocampus
Subtitle of host publicationHealth, Psychopathology, and Brain Disease
PublisherElsevier Inc.
Pages249-275
Number of pages27
ISBN (Electronic)9780128019924
ISBN (Print)9780128019771
DOIs
Publication statusPublished - 15 Apr 2016

Keywords

  • Adult neurogenesis
  • Hippocampus
  • Neurological disorders
  • Subventricular zone
  • Therapeutic treatment

ASJC Scopus subject areas

  • Neuroscience(all)

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