@inproceedings{5fb303f24fd54802bfdaa570b2213b4d,
title = "Nanoporous alumina membrane and nanoparticle based microfluidic sensing platform for direct DNA detection",
abstract = "Nucleic acids based detection has become increasingly important for biomedical diagnostics, environmental monitoring and food screening. In this paper, a nanoporous alumina membrane and nanoparticles based sensing platform has been developed for direct DNA detection. Single stranded DNA (ssDNA) was first covalently immobilized on the nanopore walls via (3-glycidoxypropyl) trimethoxysilane (GPMS). Double strand DNA (dsDNA) hybridization in the nanopores induced blockage in the nanopores, which could be detected by electrochemical impedance spectroscopy (EIS). The blockage signal was then amplified by DNA with gold nanoparticles (AuNPs) and silver catalytic deposition method. This platform is promising for simple, rapid and sensitive DNA detection.",
keywords = "DNA detection, electrochemical impedance spectroscopy, nanoparticles, Nanoporous alumina membrane",
author = "Ye, \{W. W.\} and Shi, \{J. Y.\} and Chan, \{C. Y.\} and Xiao, \{L. D.\} and M. Yang",
year = "2013",
month = jun,
day = "16",
doi = "10.1109/Transducers.2013.6627003",
language = "English",
isbn = "9781467359818",
series = "2013 Transducers and Eurosensors XXVII: The 17th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS 2013",
pages = "1255--1258",
booktitle = "2013 Transducers and Eurosensors XXVII",
note = "2013 17th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS 2013 ; Conference date: 16-06-2013 Through 20-06-2013",
}