Abstract
Nanoliter-droplet breakup in either symmetrically or asymmetrically confined T-shaped junctions is experimentally studied. The critical condition with which nanoliter droplets will break equally is theoretically analyzed based on the pressure-driven mechanism. The scaling analysis is experimentally confirmed, implying that the droplet breakup in a confined T-shaped junction is a pressure-driven process when the capillary number is less than ~0.1. A semi-empirical correlation is obtained for predicting the equal breakup in symmetric T-shaped junctions. The critical condition is found to be dependent on the initial droplet length, channel depth and capillary number. Besides the equal breakup of nanoliter droplets, a new droplet breakup pattern, unequal breakup, is observed in the symmetric T-shaped junction. In asymmetric T-shaped junctions the nanoliter-droplet breakup is found to be very difficult.
Original language | English |
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Pages (from-to) | 471-479 |
Number of pages | 9 |
Journal | Current Nanoscience |
Volume | 7 |
Issue number | 3 |
DOIs | |
Publication status | Published - Jun 2011 |
Externally published | Yes |
Keywords
- Confined t-shaped junction
- Critical condition
- Droplet breakup
- Nanoliter droplet
ASJC Scopus subject areas
- Biotechnology
- Bioengineering
- Medicine (miscellaneous)
- Biomedical Engineering
- Pharmaceutical Science