N-terminal α-amino group modification of peptides by an oxime formation-exchange reaction sequence

Karen Ka Yan Kung, Kong Fan Wong, King Chi Leung, Man Kin Wong

Research output: Journal article publicationJournal articleAcademic researchpeer-review

21 Citations (Scopus)

Abstract

A site-specific and efficient method for N-terminal modification of peptides using oxone for selective oxidation of N-terminal α-amino groups of peptides to oximes followed by transoximation with O-substituted hydroxylamines has been developed.
Original languageEnglish
Pages (from-to)6888-6890
Number of pages3
JournalChemical Communications
Volume49
Issue number61
DOIs
Publication statusPublished - 7 Aug 2013

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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