Multiplexed protein arrays enabled by polymer pen lithography: Addressing the inking challenge

Zijian Zheng, Weston L. Daniel, Louise R. Giam, Fengwei Huo, Andrew J. Senesi, Gengfeng Zheng, Chad A. Mirkin

Research output: Journal article publicationJournal articleAcademic researchpeer-review

94 Citations (Scopus)


High-end printer: A novel way of using a polymer pen lithography (PPL) array mould to localize different inks on the pens of a PPL array has been developed. This technique allows for rapid pen inking and subsequent generation of multiplexed patterns of up to 150 000 nanoand microscale protein features per second (see picture). It is a general approach, which in principle can be extended to any substance that can be transported by PPL. KGaA.
Original languageEnglish
Pages (from-to)7626-7629
Number of pages4
JournalAngewandte Chemie - International Edition
Issue number41
Publication statusPublished - 28 Sep 2009


  • Inks
  • Multiplex techniques
  • Patterning
  • Polymer pen lithography
  • Protein arrays

ASJC Scopus subject areas

  • Chemistry(all)
  • Catalysis
  • Medicine(all)

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