Multifunctional layered black phosphorene-based nanoplatform for disease diagnosis and treatment: a review

Xiazi Huang, Yingying Zhou, Chi Man Woo, Yue Pan, Liming Nie, Puxiang Lai (Corresponding Author)

Research output: Journal article publicationReview articleAcademic researchpeer-review

10 Citations (Scopus)


As an outstanding two-dimensional material, black phosphorene, has attracted significant attention in the biomedicine field due to its large surface area, strong optical absorption, distinct bioactivity, excellent biocompatibility, and high biodegradability. In this review, the preparation and properties of black phosphorene are summarized first. Thereafter, black phosphorene-based multifunctional platforms employed for the diagnosis and treatment of diseases, including cancer, bone injuries, brain diseases, progressive oxidative diseases, and kidney injury, are reviewed in detail. This review provides a better understanding of the exciting properties of black phosphorene, such as its high drug-loading efficiency, photothermal conversion capability, high 1O2 generation efficiency, and high electrical conductivity, as well as how these properties can be exploited in biomedicine. Finally, the research perspectives of black phosphorene are discussed.[Figure not available: see fulltext.]

Original languageEnglish
Pages (from-to)327-351
JournalFrontiers of Optoelectronics
Issue number4
Publication statusPublished - 26 Nov 2020


  • bioimaging
  • black phosphorus (BP)
  • bone regeneration
  • cancer therapy
  • delivery nanoplatform

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Electrical and Electronic Engineering


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