Multifocal ERG changes in glaucoma

Research output: Journal article publicationJournal articleAcademic researchpeer-review

64 Citations (Scopus)


The multifocal electroretinogram (MERG) can assess regional retinal responses using analysis which gives both first-order and second-order nonlinear responses from multiple retinal regions. The retinal responses from both types of analysis showed amplitude reduction in glaucoma, suggesting that the outer and inner retinal layers are affected. These findings are in accord with the damage which has been reported in advanced glaucoma. The macular response showed a larger amplitude reduction in b-waves (first-order response) and N2P (second-order response) than did peripheral retinal responses. This indicates that loss of macular response is an important sign in glaucoma.
Original languageEnglish
Pages (from-to)306-316
Number of pages11
JournalOphthalmic and Physiological Optics
Issue number4
Publication statusPublished - 1 Jul 1999

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems
  • General Health Professions


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