TY - JOUR
T1 - Monitoring of Curve Progression in Patients with Adolescent Idiopathic Scoliosis Using 3-D Ultrasound
AU - Lai, Kelly Ka Lee
AU - Lee, Timothy Tin Yan
AU - Lau, Heidi Hin Ting
AU - Chu, Winnie Chiu Wing
AU - Cheng, Jack Chun Yiu
AU - Castelein, René Marten
AU - Schlösser, Tom P.C.
AU - Lam, Tsz Ping
AU - Zheng, Yong Ping
N1 - Publisher Copyright:
© 2023 The Authors
PY - 2024/3
Y1 - 2024/3
N2 - Objective: The aim of the work described here was to determine whether 3-D ultrasound can provide results comparable to those of conventional X-ray examination in assessing curve progression in patients with adolescent idiopathic scoliosis (AIS). Methods: One hundred thirty-six participants with AIS (42 males and 94 females; age range: 10–18 y, mean age: 14.1 ± 1.9 y) with scoliosis of different severity (Cobb angle range: 10º– 85º, mean: of 24.3 ± 14.4º) were included. Each participant underwent biplanar low-dose X-ray EOS and 3-D ultrasound system scanning with the same posture on the same date. Participants underwent the second assessment at routine clinical follow-up. Manual measurements of scoliotic curvature on ultrasound coronal projection images and posterior–anterior radiographs were expressed as the ultrasound curve angle (UCA) and radiographic Cobb angle (RCA), respectively. RCA and UCA increments ≥5º represented a scoliosis progression detected by X-ray assessment and 3-D ultrasound assessment, respectively. Results: The sensitivity and specificity of UCA measurement in detecting scoliosis progression were 0.93 and 0.90, respectively. The negative likelihood ratio of the diagnostic test for scoliosis progression by the 3-D ultrasound imaging system was 0.08. Conclusion: The 3-D ultrasound imaging method is a valid technique for detecting coronal curve progression as compared with conventional radiography in follow-up of AIS. Substituting conventional radiography with 3-D ultrasound is effective in reducing the radiation dose to which AIS patients are exposed during their follow-up examinations.
AB - Objective: The aim of the work described here was to determine whether 3-D ultrasound can provide results comparable to those of conventional X-ray examination in assessing curve progression in patients with adolescent idiopathic scoliosis (AIS). Methods: One hundred thirty-six participants with AIS (42 males and 94 females; age range: 10–18 y, mean age: 14.1 ± 1.9 y) with scoliosis of different severity (Cobb angle range: 10º– 85º, mean: of 24.3 ± 14.4º) were included. Each participant underwent biplanar low-dose X-ray EOS and 3-D ultrasound system scanning with the same posture on the same date. Participants underwent the second assessment at routine clinical follow-up. Manual measurements of scoliotic curvature on ultrasound coronal projection images and posterior–anterior radiographs were expressed as the ultrasound curve angle (UCA) and radiographic Cobb angle (RCA), respectively. RCA and UCA increments ≥5º represented a scoliosis progression detected by X-ray assessment and 3-D ultrasound assessment, respectively. Results: The sensitivity and specificity of UCA measurement in detecting scoliosis progression were 0.93 and 0.90, respectively. The negative likelihood ratio of the diagnostic test for scoliosis progression by the 3-D ultrasound imaging system was 0.08. Conclusion: The 3-D ultrasound imaging method is a valid technique for detecting coronal curve progression as compared with conventional radiography in follow-up of AIS. Substituting conventional radiography with 3-D ultrasound is effective in reducing the radiation dose to which AIS patients are exposed during their follow-up examinations.
KW - 3-D ultrasound
KW - Adolescent idiopathic scoliosis
KW - Scoliosis
KW - Scoliosis progression
KW - Spine curvature
UR - http://www.scopus.com/inward/record.url?scp=85180584849&partnerID=8YFLogxK
U2 - 10.1016/j.ultrasmedbio.2023.11.011
DO - 10.1016/j.ultrasmedbio.2023.11.011
M3 - Journal article
C2 - 38114347
AN - SCOPUS:85180584849
SN - 0301-5629
VL - 50
SP - 384
EP - 393
JO - Ultrasound in Medicine and Biology
JF - Ultrasound in Medicine and Biology
IS - 3
ER -