Molecular characterization of Escherichia coli isolates carrying MCR-1, FOSA3, and extended-spectrum-β lactamase genes from food samples in China

Xiaobo Liu; Ruichao Li; Zhiwei Zheng; Kaichao Chen; Miaomiao Xie; Edward Wai Chi Chan; Shu Geng; Sheng Chen

doi:10.1128/AAC.00064-17

Molecular characterization of Escherichia coli isolates carrying MCR-1, FOSA3, and extended-spectrum-β lactamase genes from food samples in China

Xiaobo Liu
, Ruichao Li
, Zhiwei Zheng
, Kaichao Chen
, Miaomiao Xie
, Edward Wai Chi Chan
, Shu Geng
, Sheng Chen

The Hong Kong Polytechnic University

Research output: Journal article publication › Journal article › Academic research › peer-review

23 Citations (Scopus)

Abstract

This study surveyed the prevalence of mcr-1 in extended-spectrum- lactamase (ESBL)-producing Escherichia coli strains of food origin in China and identified strains that carried mcr-1, fosA3, and ESBL genes, which were carried in various plasmids. The mcr-1 and ESBL genes could be cotransferred by one or more types of plasmids. The presence of these multidrug-resistant E. coli strains in food products might pose a huge threat to public health.

Original language	English
Article number	e00064-17
Journal	Antimicrobial Agents and Chemotherapy
Volume	61
Issue number	6
DOIs	https://doi.org/10.1128/AAC.00064-17
Publication status	Published - 1 Jun 2017

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Circular intermediate
Esbl-producing e. coli
Fosa3
Mcr-1
Plasmids
Tn6330
Transmission

ASJC Scopus subject areas

Pharmacology
Pharmacology (medical)
Infectious Diseases

More information

10.1128/AAC.00064-17

Cite this

@article{9246840b75dc4baf83d0f6db32e9d628,

title = "Molecular characterization of Escherichia coli isolates carrying MCR-1, FOSA3, and extended-spectrum-β lactamase genes from food samples in China",

abstract = "This study surveyed the prevalence of mcr-1 in extended-spectrum- lactamase (ESBL)-producing Escherichia coli strains of food origin in China and identified strains that carried mcr-1, fosA3, and ESBL genes, which were carried in various plasmids. The mcr-1 and ESBL genes could be cotransferred by one or more types of plasmids. The presence of these multidrug-resistant E. coli strains in food products might pose a huge threat to public health.",

keywords = "Circular intermediate, Esbl-producing e. coli, Fosa3, Mcr-1, Plasmids, Tn6330, Transmission",

author = "Xiaobo Liu and Ruichao Li and Zhiwei Zheng and Kaichao Chen and Miaomiao Xie and Chan, \{Edward Wai Chi\} and Shu Geng and Sheng Chen",

year = "2017",

month = jun,

day = "1",

doi = "10.1128/AAC.00064-17",

language = "English",

volume = "61",

journal = "Antimicrobial Agents and Chemotherapy",

issn = "0066-4804",

publisher = "American Society for Microbiology",

number = "6",

}

Molecular characterization of Escherichia coli isolates carrying MCR-1, FOSA3, and extended-spectrum-β lactamase genes from food samples in China. / Liu, Xiaobo; Li, Ruichao; Zheng, Zhiwei et al.
In: Antimicrobial Agents and Chemotherapy, Vol. 61, No. 6, e00064-17, 01.06.2017.

Research output: Journal article publication › Journal article › Academic research › peer-review

TY - JOUR

T1 - Molecular characterization of Escherichia coli isolates carrying MCR-1, FOSA3, and extended-spectrum-β lactamase genes from food samples in China

AU - Liu, Xiaobo

AU - Li, Ruichao

AU - Zheng, Zhiwei

AU - Chen, Kaichao

AU - Xie, Miaomiao

AU - Chan, Edward Wai Chi

AU - Geng, Shu

AU - Chen, Sheng

PY - 2017/6/1

Y1 - 2017/6/1

N2 - This study surveyed the prevalence of mcr-1 in extended-spectrum- lactamase (ESBL)-producing Escherichia coli strains of food origin in China and identified strains that carried mcr-1, fosA3, and ESBL genes, which were carried in various plasmids. The mcr-1 and ESBL genes could be cotransferred by one or more types of plasmids. The presence of these multidrug-resistant E. coli strains in food products might pose a huge threat to public health.

AB - This study surveyed the prevalence of mcr-1 in extended-spectrum- lactamase (ESBL)-producing Escherichia coli strains of food origin in China and identified strains that carried mcr-1, fosA3, and ESBL genes, which were carried in various plasmids. The mcr-1 and ESBL genes could be cotransferred by one or more types of plasmids. The presence of these multidrug-resistant E. coli strains in food products might pose a huge threat to public health.

KW - Circular intermediate

KW - Esbl-producing e. coli

KW - Fosa3

KW - Mcr-1

KW - Plasmids

KW - Tn6330

KW - Transmission

UR - https://www.scopus.com/pages/publications/85019531158

U2 - 10.1128/AAC.00064-17

DO - 10.1128/AAC.00064-17

M3 - Journal article

C2 - 28373188

SN - 0066-4804

VL - 61

JO - Antimicrobial Agents and Chemotherapy

JF - Antimicrobial Agents and Chemotherapy

IS - 6

M1 - e00064-17

ER -

Molecular characterization of Escherichia coli isolates carrying MCR-1, FOSA3, and extended-spectrum-β lactamase genes from food samples in China

Abstract

UN SDGs

Keywords

ASJC Scopus subject areas

More information

Other files and links

Fingerprint

Cite this