Molecular characterization of Escherichia coli isolates carrying MCR-1, FOSA3, and extended-spectrum-β lactamase genes from food samples in China

Xiaobo Liu; Ruichao Li; Zhiwei Zheng; Kaichao Chen; Miaomiao Xie; Edward Wai Chi Chan; Shu Geng; Sheng Chen

doi:10.1128/AAC.00064-17

Molecular characterization of Escherichia coli isolates carrying MCR-1, FOSA3, and extended-spectrum-β lactamase genes from food samples in China

Xiaobo Liu, Ruichao Li, Zhiwei Zheng, Kaichao Chen, Miaomiao Xie, Edward Wai Chi Chan, Shu Geng, Sheng Chen

The Hong Kong Polytechnic University

Research output: Journal article publication › Journal article › Academic research › peer-review

21 Citations (Scopus)

Abstract

This study surveyed the prevalence of mcr-1 in extended-spectrum- lactamase (ESBL)-producing Escherichia coli strains of food origin in China and identified strains that carried mcr-1, fosA3, and ESBL genes, which were carried in various plasmids. The mcr-1 and ESBL genes could be cotransferred by one or more types of plasmids. The presence of these multidrug-resistant E. coli strains in food products might pose a huge threat to public health.

Original language	English
Article number	e00064-17
Journal	Antimicrobial Agents and Chemotherapy
Volume	61
Issue number	6
DOIs	https://doi.org/10.1128/AAC.00064-17
Publication status	Published - 1 Jun 2017

Keywords

Circular intermediate
Esbl-producing e. coli
Fosa3
Mcr-1
Plasmids
Tn6330
Transmission

ASJC Scopus subject areas

Pharmacology
Pharmacology (medical)
Infectious Diseases

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

More information

10.1128/AAC.00064-17

Cite this

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title = "Molecular characterization of Escherichia coli isolates carrying MCR-1, FOSA3, and extended-spectrum-β lactamase genes from food samples in China",

abstract = "This study surveyed the prevalence of mcr-1 in extended-spectrum- lactamase (ESBL)-producing Escherichia coli strains of food origin in China and identified strains that carried mcr-1, fosA3, and ESBL genes, which were carried in various plasmids. The mcr-1 and ESBL genes could be cotransferred by one or more types of plasmids. The presence of these multidrug-resistant E. coli strains in food products might pose a huge threat to public health.",

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Molecular characterization of Escherichia coli isolates carrying MCR-1, FOSA3, and extended-spectrum-β lactamase genes from food samples in China. / Liu, Xiaobo; Li, Ruichao; Zheng, Zhiwei et al.
In: Antimicrobial Agents and Chemotherapy, Vol. 61, No. 6, e00064-17, 01.06.2017.

Research output: Journal article publication › Journal article › Academic research › peer-review

TY - JOUR

T1 - Molecular characterization of Escherichia coli isolates carrying MCR-1, FOSA3, and extended-spectrum-β lactamase genes from food samples in China

AU - Liu, Xiaobo

AU - Li, Ruichao

AU - Zheng, Zhiwei

AU - Chen, Kaichao

AU - Xie, Miaomiao

AU - Chan, Edward Wai Chi

AU - Geng, Shu

AU - Chen, Sheng

PY - 2017/6/1

Y1 - 2017/6/1

N2 - This study surveyed the prevalence of mcr-1 in extended-spectrum- lactamase (ESBL)-producing Escherichia coli strains of food origin in China and identified strains that carried mcr-1, fosA3, and ESBL genes, which were carried in various plasmids. The mcr-1 and ESBL genes could be cotransferred by one or more types of plasmids. The presence of these multidrug-resistant E. coli strains in food products might pose a huge threat to public health.

AB - This study surveyed the prevalence of mcr-1 in extended-spectrum- lactamase (ESBL)-producing Escherichia coli strains of food origin in China and identified strains that carried mcr-1, fosA3, and ESBL genes, which were carried in various plasmids. The mcr-1 and ESBL genes could be cotransferred by one or more types of plasmids. The presence of these multidrug-resistant E. coli strains in food products might pose a huge threat to public health.

KW - Circular intermediate

KW - Esbl-producing e. coli

KW - Fosa3

KW - Mcr-1

KW - Plasmids

KW - Tn6330

KW - Transmission

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DO - 10.1128/AAC.00064-17

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SN - 0066-4804

VL - 61

JO - Antimicrobial Agents and Chemotherapy

JF - Antimicrobial Agents and Chemotherapy

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ER -

Molecular characterization of Escherichia coli isolates carrying MCR-1, FOSA3, and extended-spectrum-β lactamase genes from food samples in China

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

More information

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