Molecular characterization of Escherichia coli isolates carrying MCR-1, FOSA3, and extended-spectrum-β lactamase genes from food samples in China

Xiaobo Liu, Ruichao Li, Zhiwei Zheng, Kaichao Chen, Miaomiao Xie, Edward Wai Chi Chan, Shu Geng, Sheng Chen

Research output: Journal article publicationJournal articleAcademic researchpeer-review

14 Citations (Scopus)


This study surveyed the prevalence of mcr-1 in extended-spectrum- lactamase (ESBL)-producing Escherichia coli strains of food origin in China and identified strains that carried mcr-1, fosA3, and ESBL genes, which were carried in various plasmids. The mcr-1 and ESBL genes could be cotransferred by one or more types of plasmids. The presence of these multidrug-resistant E. coli strains in food products might pose a huge threat to public health.
Original languageEnglish
Article numbere00064-17
JournalAntimicrobial Agents and Chemotherapy
Issue number6
Publication statusPublished - 1 Jun 2017


  • Circular intermediate
  • Esbl-producing e. coli
  • Fosa3
  • Mcr-1
  • Plasmids
  • Tn6330
  • Transmission

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)
  • Infectious Diseases

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