Modular synthesis of propargylamine modified cyclodextrins by a gold(iii)-catalyzed three-component coupling reaction

Tsz Wai Hui; Jian Fang Cui; Man Kin Wong

doi:10.1039/c7ra00249a

Modular synthesis of propargylamine modified cyclodextrins by a gold(iii)-catalyzed three-component coupling reaction

Tsz Wai Hui, Jian Fang Cui, Man Kin Wong

Research output: Journal article publication › Journal article › Academic research › peer-review

13 Citations (Scopus)

Abstract

An efficient modular approach for the synthesis of propargylamine modified β-cyclodextrins has been developed. Using mono-(6-benzylamino-6-deoxy)-β-cyclodextrins, formaldehyde, and alkynes, mono-(6-(benzylpropargyl)amino-6-deoxy)-β-cyclodextrins have been synthesized through a three-component coupling reaction catalyzed by gold(iii) salt in water at 40 °C.

Original language	English
Pages (from-to)	14477-14480
Number of pages	4
Journal	RSC Advances
Volume	7
Issue number	24
DOIs	https://doi.org/10.1039/c7ra00249a
Publication status	Published - 1 Jan 2017

ASJC Scopus subject areas

Chemistry(all)
Chemical Engineering(all)

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10.1039/c7ra00249a

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AU - Cui, Jian Fang

AU - Wong, Man Kin

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AB - An efficient modular approach for the synthesis of propargylamine modified β-cyclodextrins has been developed. Using mono-(6-benzylamino-6-deoxy)-β-cyclodextrins, formaldehyde, and alkynes, mono-(6-(benzylpropargyl)amino-6-deoxy)-β-cyclodextrins have been synthesized through a three-component coupling reaction catalyzed by gold(iii) salt in water at 40 °C.

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U2 - 10.1039/c7ra00249a

DO - 10.1039/c7ra00249a

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JO - RSC Advances

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ER -

Modular synthesis of propargylamine modified cyclodextrins by a gold(iii)-catalyzed three-component coupling reaction

Abstract

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