Modelling ECT effects by connectivity changes in cortical neural networks

  • Y. Gu (Corresponding Author)
  • , G. Halnes
  • , H. Liljenström
  • , D. von Rosen
  • , B. Wahlund
  • , H. Liang

Research output: Journal article publicationJournal articleAcademic researchpeer-review

Abstract

Biomathematical methods were applied to investigate how cortical neurodynamics depends on network connectivity. In particular, we study changes in the EEG pattern of depressed patients, following electroconvulsive therapy (ECT). The aim is to gain a better understanding of the neural mechanisms responsible for these changes, which include clear phase shifts in the EEG dynamics. This understanding is intended to provide clinical guidance in predicting ECT dose and response in depressed patients.

Original languageEnglish
Pages (from-to)1341-1347
Number of pages7
JournalNeurocomputing
Volume69
Issue number10-12
DOIs
Publication statusPublished - 10 Feb 2006
Externally publishedYes

Keywords

  • Clinical data
  • EEG
  • Fitzhugh-Nagumo neurons
  • Neo-cortical network
  • Neurodynamics

ASJC Scopus subject areas

  • Computer Science Applications
  • Cognitive Neuroscience
  • Artificial Intelligence

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