Modeling hepatitis B virus X-induced hepatocellular carcinoma in mice with the sleeping beauty transposon system

Keyphrases

• Hepatocellular Carcinoma 100%
• Sleeping Beauty Transposon 100%
• Hepatitis B Virus 100%
• Hepatitis B Virus X 100%
• Constitutively Active 60%
• Fumarylacetoacetate Hydrolase 60%
• Liver Hyperplasia 60%
• Liver 40%
• Hepatocytes 40%
• Mutant Mice 40%
• Repopulation 40%
• Hyperplasia 40%
• Delivery System 20%
• Complementary DNA (cDNA) 20%
• Co-expression 20%
• Tumorigenicity 20%
• Oncogene 20%
• Tumor Suppressor Gene 20%
• Viral 20%
• Wnt Signaling Pathway 20%
• Catenin 20%
• Short Hairpin RNA (shRNA) 20%
• RAS Oncogene 20%
• Neuroblastoma 20%
• Transposon Vector 20%
• Genetic Contribution 20%
• Hepatitis B Virus X Gene 20%
• Hydrodynamic Delivery 20%
• Liver Tumorigenesis 20%
• Protein 53 20%
• Hydrodynamic Tail Vein Injection 20%
• Oncogene Cooperation 20%
• Liver Inflammation 20%
• In Vivo System 20%

Biochemistry, Genetics and Molecular Biology

• Transposable Element 100%
• Hepatitis B Virus 100%
• Fumarylacetoacetate Hydrolase 27%
• Genetics 18%
• Mouse Mutant 18%
• Hepatocyte 18%
• Cooperation 9%
• Oncogene 9%
• Wnt Signaling Pathway 9%
• Animal Models 9%
• Complementary DNA 9%
• Tumor Suppressor Gene 9%
• Transgene 9%
• Hydrodynamics Based Transfection 9%
• Oncogene Ras 9%
• Carcinogenesis 9%
• Catenin 9%
• Small Hairpin RNA 9%

Pharmacology, Toxicology and Pharmaceutical Science

• Liver Cell Carcinoma 100%
• Hepatitis B Virus 100%
• Fumarylacetoacetase 27%
• Liver Hyperplasia 27%
• Mouse Mutant 18%
• Hyperplasia 18%
• Neuroblastoma 9%
• Carcinogenicity 9%
• Short Hairpin RNA 9%
• Catenin 9%
• Disease 9%
• Carcinogenesis 9%
• Complementary DNA 9%
• Hepatitis 9%
• Tumor Suppressor Protein 9%