Microencapsulation of Traditional Chinese Herbs-PentaHerbs extracts and potential application in healthcare textiles

Patrick Chi Leung Hui; Wen Yi Wang; Chi Wai Kan; Frency Sau Fun Ng; Elaine Wat; Vanilla Xin Zhang; Chung Lap Chan; Clara Bik San Lau; Ping Chung Leung

doi:10.1016/j.colsurfb.2013.05.036

Microencapsulation of Traditional Chinese Herbs-PentaHerbs extracts and potential application in healthcare textiles

Patrick Chi Leung Hui, Wen Yi Wang, Chi Wai Kan, Frency Sau Fun Ng, Elaine Wat, Vanilla Xin Zhang, Chung Lap Chan, Clara Bik San Lau, Ping Chung Leung

The Hong Kong Polytechnic University

Research output: Journal article publication › Journal article › Academic research › peer-review

50 Citations (Scopus)

Abstract

In this work, Traditional Chinese Herbs (TCH)-PentaHerbs-was successfully microencapsulated in chitosan-sodium alginate (CSA) blend matrix using emulsion-chemical cross-linking method and the final product was characterised with regard to structure, surface morphology, particle size, in vitro drug release and skin toxicity by means of Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), laser diffraction particle size analysis, high performance liquid chromatography (HPLC) and methyl thiazolyl tetrazolium (MTT) and lactate dehydrogenase (LDH) release assays respectively. Results showed that the microcapsules were in spherical form with diameter mostly in the range of 3-18. μm and that the release performance of the microcapsules was influenced by pH value of phosphate buffer solution (PBS). The microcapsules had no toxic effects on cells and were successfully grafted onto the surface of cotton fabrics. These results indicated that PentaHerbs loaded CSA microcapsule may possess potential application in clinical treatment of atopic dermatitis (AD).

Original language	English
Pages (from-to)	156-161
Number of pages	6
Journal	Colloids and Surfaces B: Biointerfaces
Volume	111
DOIs	https://doi.org/10.1016/j.colsurfb.2013.05.036
Publication status	Published - 1 Nov 2013

Keywords

Atopic dermatitis
Healthcare textiles
Microencapsulation
PentaHerbs

ASJC Scopus subject areas

Biotechnology
Surfaces and Interfaces
Physical and Theoretical Chemistry
Colloid and Surface Chemistry

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10.1016/j.colsurfb.2013.05.036

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title = "Microencapsulation of Traditional Chinese Herbs-PentaHerbs extracts and potential application in healthcare textiles",

abstract = "In this work, Traditional Chinese Herbs (TCH)-PentaHerbs-was successfully microencapsulated in chitosan-sodium alginate (CSA) blend matrix using emulsion-chemical cross-linking method and the final product was characterised with regard to structure, surface morphology, particle size, in vitro drug release and skin toxicity by means of Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), laser diffraction particle size analysis, high performance liquid chromatography (HPLC) and methyl thiazolyl tetrazolium (MTT) and lactate dehydrogenase (LDH) release assays respectively. Results showed that the microcapsules were in spherical form with diameter mostly in the range of 3-18. μm and that the release performance of the microcapsules was influenced by pH value of phosphate buffer solution (PBS). The microcapsules had no toxic effects on cells and were successfully grafted onto the surface of cotton fabrics. These results indicated that PentaHerbs loaded CSA microcapsule may possess potential application in clinical treatment of atopic dermatitis (AD).",

keywords = "Atopic dermatitis, Healthcare textiles, Microencapsulation, PentaHerbs",

author = "Hui, {Patrick Chi Leung} and Wang, {Wen Yi} and Kan, {Chi Wai} and Ng, {Frency Sau Fun} and Elaine Wat and Zhang, {Vanilla Xin} and Chan, {Chung Lap} and Lau, {Clara Bik San} and Leung, {Ping Chung}",

year = "2013",

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day = "1",

doi = "10.1016/j.colsurfb.2013.05.036",

language = "English",

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AU - Hui, Patrick Chi Leung

AU - Wang, Wen Yi

AU - Kan, Chi Wai

AU - Ng, Frency Sau Fun

AU - Wat, Elaine

AU - Zhang, Vanilla Xin

AU - Chan, Chung Lap

AU - Lau, Clara Bik San

AU - Leung, Ping Chung

PY - 2013/11/1

Y1 - 2013/11/1

N2 - In this work, Traditional Chinese Herbs (TCH)-PentaHerbs-was successfully microencapsulated in chitosan-sodium alginate (CSA) blend matrix using emulsion-chemical cross-linking method and the final product was characterised with regard to structure, surface morphology, particle size, in vitro drug release and skin toxicity by means of Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), laser diffraction particle size analysis, high performance liquid chromatography (HPLC) and methyl thiazolyl tetrazolium (MTT) and lactate dehydrogenase (LDH) release assays respectively. Results showed that the microcapsules were in spherical form with diameter mostly in the range of 3-18. μm and that the release performance of the microcapsules was influenced by pH value of phosphate buffer solution (PBS). The microcapsules had no toxic effects on cells and were successfully grafted onto the surface of cotton fabrics. These results indicated that PentaHerbs loaded CSA microcapsule may possess potential application in clinical treatment of atopic dermatitis (AD).

AB - In this work, Traditional Chinese Herbs (TCH)-PentaHerbs-was successfully microencapsulated in chitosan-sodium alginate (CSA) blend matrix using emulsion-chemical cross-linking method and the final product was characterised with regard to structure, surface morphology, particle size, in vitro drug release and skin toxicity by means of Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), laser diffraction particle size analysis, high performance liquid chromatography (HPLC) and methyl thiazolyl tetrazolium (MTT) and lactate dehydrogenase (LDH) release assays respectively. Results showed that the microcapsules were in spherical form with diameter mostly in the range of 3-18. μm and that the release performance of the microcapsules was influenced by pH value of phosphate buffer solution (PBS). The microcapsules had no toxic effects on cells and were successfully grafted onto the surface of cotton fabrics. These results indicated that PentaHerbs loaded CSA microcapsule may possess potential application in clinical treatment of atopic dermatitis (AD).

KW - Atopic dermatitis

KW - Healthcare textiles

KW - Microencapsulation

KW - PentaHerbs

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DO - 10.1016/j.colsurfb.2013.05.036

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AN - SCOPUS:84879477146

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JO - Colloids and Surfaces B: Biointerfaces

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ER -

Microencapsulation of Traditional Chinese Herbs-PentaHerbs extracts and potential application in healthcare textiles

Abstract

Keywords

ASJC Scopus subject areas

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