Micro-finite element model for bone strength prediction

He Gong, Ming Zhang, Ling Qin

Research output: Chapter in book / Conference proceedingChapter in an edited book (as author)Academic researchpeer-review

1 Citation (Scopus)


A quantitative assessment of trabecular bone strength at the tissue level is essential for understanding bone failure mechanisms associated with osteoporosis, osteoarthritis, loosening of implants, and cell-mediated adaptive bone remodeling. The material properties of the trabeculae, in combination with their microarchitectures at the tissue level, determine the strength of trabecular bone. Micro-CT (computed tomography) image-based micro-finite element analysis takes most determinants of trabecular bone strength into consideration, such as the material properties of the trabeculae and their micro-architectures. Under large loading conditions, bone tissue material nonlinearity and large deformations within the trabecular network, such as bending and buckling, are important for the characterization of the apparent and tissue-level failure behaviors. In this chapter, two trabecular specimens with different microstructures are used as examples to illustrate a numerical technique that offers a better understanding of trabecular yield behaviors under different loading directions.

Original languageEnglish
Title of host publicationComputational Biomechanics of the Musculoskeletal System
PublisherCRC Press
Number of pages8
ISBN (Electronic)9781466588042
ISBN (Print)9781466588035
Publication statusPublished - 1 Jan 2014

ASJC Scopus subject areas

  • Medicine(all)


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