@article{ace202df89e94fbca2300b61a7dda77c,
title = "Metal-Free, Acid/Phosphine-Induced Regioselective Thiolation of p-Quinone Methides with Sodium Aryl/Alkyl Sulfinates",
abstract = "A simple and efficient method for the regioselective thiolation of p-quinone methides with sodium aryl/alkyl sulfinates has been established using an acid/phosphine-induced radical route under transition-metal-free conditions. A broad range of sodium aryl/alkyl sulfinates and p-quinone methides (p-QMs) are compatible for the reaction, giving the expected products with good to excellent yields. Control experiments were also performed to gain insights into the generation mechanism of thiyl radicals and hydrogen-atom transfer process. This protocol provides a safe and feasible way for the formation of carbon-sulfur bonds. ",
author = "Biquan Xiong and Shipan Xu and Yu Liu and Tang, {Ke Wen} and Wong, {Wai Yeung}",
note = "Funding Information: This work was supported by the National Natural Science Foundation of China (21606080), Natural Science Foundation of Hunan Province (2019JJ50203), Scientific Research Fund of the Hunan Provincial Education Department (19A197), Innovation Research Group Project of the Natural Science Foundation of Hunan Province (No. 2020JJ1004), and Hunan Provincial Innovation Foundation for Postgraduate (CX20201132). W.-Y.W. thanks the Hong Kong Polytechnic University (1-ZE1C) and the Endowed Professorship in Energy from Ms Clarea Au (847S) for financial support. Publisher Copyright: {\textcopyright} 2021 American Chemical Society. All rights reserved.",
year = "2021",
month = jan,
day = "15",
doi = "10.1021/acs.joc.0c02390",
language = "English",
volume = "86",
pages = "1516--1527",
journal = "Journal of Organic Chemistry",
issn = "0022-3263",
publisher = "American Chemical Society",
number = "2",
}