Mechanism of anticancer effects of antimicrobial peptides

Xuan Liu; Yi Li; Zhi Li; Xi Qian Lan; Hang Mei Polly Leung; Jia Shen Li; Mo Yang; Ko Frank; Ling Qin

Mechanism of anticancer effects of antimicrobial peptides

Xuan Liu, Yi Li, Zhi Li, Xi Qian Lan, Hang Mei Polly Leung, Jia Shen Li, Mo Yang, Ko Frank, Ling Qin

Research output: Chapter in book / Conference proceeding › Conference article published in proceeding or book › Academic research › peer-review

Abstract

Antimicrobial peptides (AMPs) were first known as a group of innate immune products that mainly targets on the invading pathogens among multiple species. The essential mechanisms of action of AMPs toward microbial cells have been reported as electrostatic attraction and hydrophobic interaction between AMPs (cationic AMPs) and microbial cell membranes. These effects also contributed to the potential mechanism of anticancer activities of AMPs as well. The membrane difference between cancer cells and normal cells are believed to play significant roles in AMPs orienting process. Membrane selective targeting properties made AMPs promising candidates for alternative approach to solve the problems from anticancer drug resistance.

Original language	English
Title of host publication	Textile Bioengineering and Informatics Symposium Proceedings 2014 - 7th Textile Bioengineering and Informatics Symposium, TBIS 2014, in conjunction with the 5th Asian Protective Clothing Conference, APCC 2014
Publisher	Binary Information Press
Pages	243-251
Number of pages	9
Publication status	Published - 1 Jan 2014
Event	7th Textile Bioengineering and Informatics Symposium, TBIS 2014, in conjunction with the 5th Asian Protective Clothing Conference, APCC 2014 - The Hong Kong Polytechnic University, Hong Kong, Hong Kong Duration: 6 Aug 2014 → 8 Aug 2014

Conference

Conference	7th Textile Bioengineering and Informatics Symposium, TBIS 2014, in conjunction with the 5th Asian Protective Clothing Conference, APCC 2014
Country/Territory	Hong Kong
City	Hong Kong
Period	6/08/14 → 8/08/14

Keywords

Anticancer activity
Anticancer drug resistance
Antimicrobial peptides
Electrostatic attraction
Hydrophobic interaction

ASJC Scopus subject areas

Bioengineering
Biomaterials

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Cite this

Liu, X., Li, Y., Li, Z., Lan, X. Q., Leung, H. M. P., Li, J. S., Yang, M., Frank, K., & Qin, L. (2014). Mechanism of anticancer effects of antimicrobial peptides. In Textile Bioengineering and Informatics Symposium Proceedings 2014 - 7th Textile Bioengineering and Informatics Symposium, TBIS 2014, in conjunction with the 5th Asian Protective Clothing Conference, APCC 2014 (pp. 243-251). Binary Information Press.

@inproceedings{7af56b996bb74c3cb3716694fddeda9f,

title = "Mechanism of anticancer effects of antimicrobial peptides",

abstract = "Antimicrobial peptides (AMPs) were first known as a group of innate immune products that mainly targets on the invading pathogens among multiple species. The essential mechanisms of action of AMPs toward microbial cells have been reported as electrostatic attraction and hydrophobic interaction between AMPs (cationic AMPs) and microbial cell membranes. These effects also contributed to the potential mechanism of anticancer activities of AMPs as well. The membrane difference between cancer cells and normal cells are believed to play significant roles in AMPs orienting process. Membrane selective targeting properties made AMPs promising candidates for alternative approach to solve the problems from anticancer drug resistance.",

keywords = "Anticancer activity, Anticancer drug resistance, Antimicrobial peptides, Electrostatic attraction, Hydrophobic interaction",

author = "Xuan Liu and Yi Li and Zhi Li and Lan, {Xi Qian} and Leung, {Hang Mei Polly} and Li, {Jia Shen} and Mo Yang and Ko Frank and Ling Qin",

year = "2014",

month = jan,

day = "1",

language = "English",

pages = "243--251",

booktitle = "Textile Bioengineering and Informatics Symposium Proceedings 2014 - 7th Textile Bioengineering and Informatics Symposium, TBIS 2014, in conjunction with the 5th Asian Protective Clothing Conference, APCC 2014",

publisher = "Binary Information Press",

note = "7th Textile Bioengineering and Informatics Symposium, TBIS 2014, in conjunction with the 5th Asian Protective Clothing Conference, APCC 2014 ; Conference date: 06-08-2014 Through 08-08-2014",

}

Liu, X, Li, Y, Li, Z, Lan, XQ, Leung, HMP, Li, JS, Yang, M, Frank, K & Qin, L 2014, Mechanism of anticancer effects of antimicrobial peptides. in Textile Bioengineering and Informatics Symposium Proceedings 2014 - 7th Textile Bioengineering and Informatics Symposium, TBIS 2014, in conjunction with the 5th Asian Protective Clothing Conference, APCC 2014. Binary Information Press, pp. 243-251, 7th Textile Bioengineering and Informatics Symposium, TBIS 2014, in conjunction with the 5th Asian Protective Clothing Conference, APCC 2014, Hong Kong, Hong Kong, 6/08/14.

Mechanism of anticancer effects of antimicrobial peptides. / Liu, Xuan; Li, Yi; Li, Zhi et al.
Textile Bioengineering and Informatics Symposium Proceedings 2014 - 7th Textile Bioengineering and Informatics Symposium, TBIS 2014, in conjunction with the 5th Asian Protective Clothing Conference, APCC 2014. Binary Information Press, 2014. p. 243-251.

Research output: Chapter in book / Conference proceeding › Conference article published in proceeding or book › Academic research › peer-review

TY - GEN

T1 - Mechanism of anticancer effects of antimicrobial peptides

AU - Liu, Xuan

AU - Li, Yi

AU - Li, Zhi

AU - Lan, Xi Qian

AU - Leung, Hang Mei Polly

AU - Li, Jia Shen

AU - Yang, Mo

AU - Frank, Ko

AU - Qin, Ling

PY - 2014/1/1

Y1 - 2014/1/1

N2 - Antimicrobial peptides (AMPs) were first known as a group of innate immune products that mainly targets on the invading pathogens among multiple species. The essential mechanisms of action of AMPs toward microbial cells have been reported as electrostatic attraction and hydrophobic interaction between AMPs (cationic AMPs) and microbial cell membranes. These effects also contributed to the potential mechanism of anticancer activities of AMPs as well. The membrane difference between cancer cells and normal cells are believed to play significant roles in AMPs orienting process. Membrane selective targeting properties made AMPs promising candidates for alternative approach to solve the problems from anticancer drug resistance.

AB - Antimicrobial peptides (AMPs) were first known as a group of innate immune products that mainly targets on the invading pathogens among multiple species. The essential mechanisms of action of AMPs toward microbial cells have been reported as electrostatic attraction and hydrophobic interaction between AMPs (cationic AMPs) and microbial cell membranes. These effects also contributed to the potential mechanism of anticancer activities of AMPs as well. The membrane difference between cancer cells and normal cells are believed to play significant roles in AMPs orienting process. Membrane selective targeting properties made AMPs promising candidates for alternative approach to solve the problems from anticancer drug resistance.

KW - Anticancer activity

KW - Anticancer drug resistance

KW - Antimicrobial peptides

KW - Electrostatic attraction

KW - Hydrophobic interaction

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M3 - Conference article published in proceeding or book

SP - 243

EP - 251

BT - Textile Bioengineering and Informatics Symposium Proceedings 2014 - 7th Textile Bioengineering and Informatics Symposium, TBIS 2014, in conjunction with the 5th Asian Protective Clothing Conference, APCC 2014

PB - Binary Information Press

T2 - 7th Textile Bioengineering and Informatics Symposium, TBIS 2014, in conjunction with the 5th Asian Protective Clothing Conference, APCC 2014

Y2 - 6 August 2014 through 8 August 2014

ER -

Mechanism of anticancer effects of antimicrobial peptides

Abstract

Conference

Keywords

ASJC Scopus subject areas

UN SDGs

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