@article{b2cd417270d54e1d83c5e37bc7ec42d9,
title = "Measurement of pulse wave signals and blood pressure by a plastic optical fiber FBG sensor",
abstract = "Fiber Bragg grating (FBG) sensors fabricated in silica optical fiber (Silica-FBG) have been used to measure the strain of human arteries as pulse wave signals. A variety of vital signs including blood pressure can be derived from these signals. However, silica optical fiber presents a safety risk because it is easily fractured. In this research, an FBG sensor fabricated in plastic optical fiber (POF-FBG) was employed to resolve this problem. Pulse wave signals were measured by POF-FBG and silica-FBG sensors for four subjects. After signal processing, a calibration curve was constructed by partial least squares regression, then blood pressure was calculated from the calibration curve. As a result, the POF-FBG sensor could measure the pulse wave signals with an signal to noise (SN) ratio at least eight times higher than the silica-FBG sensor. Further, the measured signals were substantially similar to those of an acceleration plethysmograph (APG). Blood pressure is measured with low error, but the POF-FBG APG correlation is distributed from 0.54 to 0.72, which is not as high as desired. Based on these results, pulse wave signals should be measured under a wide range of reference blood pressures to confirm the reliability of blood pressure measurement uses POF-FBG sensors.",
keywords = "Blood pressure, Fiber Bragg grating, Non-invasive measurement, Partial least squares regression, Plastic optical fiber, Pulse wave signals",
author = "Yuki Haseda and Julien Bonefacino and Tam, {Hwa Yaw} and Shun Chino and Shouhei Koyama and Hiroaki Ishizawa",
note = "Funding Information: Funding: This work was supported by JSPS KAKNHI, grant Number JP16H01805 and the Wearable Vital Signs Measurement System Development Project at Shinshu University. This work was also supported by a Grant-in-Aid for the Shinshu University Advanced Leading Graduate Program by the Ministry of Education, Culture, Sports, Science and Technology (MEXT), Japan. This research is partially supported by the Creation of a development platform for implantable/wearable medical devices by a novel physiological data integration system of the Program on Open Innovation Platform with Enterprises, Research Institute and Academia (OPERA) from the Japan Science and Technology Agency (JST), grant Number JPMJOP1722. This work was supported by the General Research Fund Project (PolyU 152207/18E) and PolyU Central Grant project 1-ZVGB. Funding Information: This work was supported by JSPS KAKNHI, grant Number JP16H01805 and the Wearable Vital Signs Measurement System Development Project at Shinshu University. This work was also supported by a Grant-in-Aid for the Shinshu University Advanced Leading Graduate Program by the Ministry of Education, Culture, Sports, Science and Technology (MEXT), Japan. This research is partially supported by the Creation of a development platform for implantable/wearable medical devices by a novel physiological data integration system of the Program on Open Innovation Platform with Enterprises, Research Institute and Academia (OPERA) from the Japan Science and Technology Agency (JST), grant Number JPMJOP1722. This work was supported by the General Research Fund Project (PolyU 152207/18E) and PolyU Central Grant project 1-ZVGB. Publisher Copyright: {\textcopyright} 2019 by the authors. Licensee MDPI, Basel, Switzerland.",
year = "2019",
month = dec,
day = "1",
doi = "10.3390/s19235088",
language = "English",
volume = "19",
journal = "Sensors (Switzerland)",
issn = "1424-8220",
publisher = "Multidisciplinary Digital Publishing Institute (MDPI)",
number = "23",
}