Massively parallel patterning of complex 2D and 3D functional polymer brushes by polymer pen lithography

Zhuang Xie, Chaojian Chen, Xuechang Zhou, Tingting Gao, Danqing Liu, Qian Miao, Zijian Zheng

Research output: Journal article publicationJournal articleAcademic researchpeer-review

48 Citations (Scopus)


We report the first demonstration of centimeter-area serial patterning of complex 2D and 3D functional polymer brushes by high-throughput polymer pen lithography. Arbitrary 2D and 3D structures of poly(glycidyl methacrylate) (PGMA) brushes are fabricated over areas as large as 2 cm × 1 cm, with a remarkable throughput being 3 orders of magnitudes higher than the state-of-the-arts. Patterned PGMA brushes are further employed as resist for fabricating Au micro/nanostructures and hard molds for the subsequent replica molding of soft stamps. On the other hand, these 2D and 3D PGMA brushes are also utilized as robust and versatile platforms for the immobilization of bioactive molecules to form 2D and 3D patterned DNA oligonucleotide and protein chips. Therefore, this low-cost, yet high-throughput "bench-top" serial fabrication method can be readily applied to a wide range of fields including micro/nanofabrication, optics and electronics, smart surfaces, and biorelated studies.
Original languageEnglish
Pages (from-to)11955-11964
Number of pages10
JournalACS Applied Materials and Interfaces
Issue number15
Publication statusPublished - 13 Aug 2014


  • biomolecular array
  • micro/nanofabrication
  • polymer brushes
  • polymer pen lithography
  • three-dimensional structures

ASJC Scopus subject areas

  • Materials Science(all)

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