TY - JOUR
T1 - Magnetic Janus origami robot for cross-scale droplet omni-manipulation
AU - Jiang, Shaojun
AU - Li, Bo
AU - Zhao, Jun
AU - Wu, Dong
AU - Zhang, Yiyuan
AU - Zhao, Zhipeng
AU - Zhang, Yiyuan
AU - Yu, Hao
AU - Shao, Kexiang
AU - Zhang, Cong
AU - Li, Rui
AU - Chen, Chao
AU - Shen, Zuojun
AU - Hu, Jie
AU - Dong, Bin
AU - Zhu, Ling
AU - Li, Jiawen
AU - Wang, Liqiu
AU - Chu, Jiaru
AU - Hu, Yanlei
N1 - Publisher Copyright:
© 2023, Springer Nature Limited.
PY - 2023/12
Y1 - 2023/12
N2 - The versatile manipulation of cross-scale droplets is essential in many fields. Magnetic excitation is widely used for droplet manipulation due to its distinguishing merits. However, facile magnetic actuation strategies are still lacked to realize versatile multiscale droplet manipulation. Here, a type of magnetically actuated Janus origami robot is readily fabricated for versatile cross-scale droplet manipulation including three-dimensional transport, merging, splitting, dispensing and release of daughter droplets, stirring and remote heating. The robot allows untethered droplet manipulation from ~3.2 nL to ~51.14 μL. It enables splitting of droplet, precise dispensing (minimum of ~3.2 nL) and release (minimum of ~30.2 nL) of daughter droplets. The combination of magnetically controlled rotation and photothermal properties further endows the robot with the ability to stir and heat droplets remotely. Finally, the application of the robot in polymerase chain reaction (PCR) is explored. The extraction and purification of nucleic acids can be successfully achieved.
AB - The versatile manipulation of cross-scale droplets is essential in many fields. Magnetic excitation is widely used for droplet manipulation due to its distinguishing merits. However, facile magnetic actuation strategies are still lacked to realize versatile multiscale droplet manipulation. Here, a type of magnetically actuated Janus origami robot is readily fabricated for versatile cross-scale droplet manipulation including three-dimensional transport, merging, splitting, dispensing and release of daughter droplets, stirring and remote heating. The robot allows untethered droplet manipulation from ~3.2 nL to ~51.14 μL. It enables splitting of droplet, precise dispensing (minimum of ~3.2 nL) and release (minimum of ~30.2 nL) of daughter droplets. The combination of magnetically controlled rotation and photothermal properties further endows the robot with the ability to stir and heat droplets remotely. Finally, the application of the robot in polymerase chain reaction (PCR) is explored. The extraction and purification of nucleic acids can be successfully achieved.
UR - http://www.scopus.com/inward/record.url?scp=85169998938&partnerID=8YFLogxK
U2 - 10.1038/s41467-023-41092-1
DO - 10.1038/s41467-023-41092-1
M3 - Journal article
C2 - 37673871
AN - SCOPUS:85169998938
SN - 2041-1723
VL - 14
JO - Nature Communications
JF - Nature Communications
IS - 1
M1 - 5455
ER -