Abstract
A lowered bone mineral density (BMD) was observed in trabecular bone in a significant number of AIS patients. The present study aims at investigating whether lower BMD is a systemic phenomenon, which would also be present in the cortical component of long bone. Subjects and Methods. 78 AIS girls (age:15-18y.o) with either moderate (Cobb: 20-40) or severe (Cobb: >40) curve and 44 age-matched controls were recruited. The BMD of the distal region and the mid-shaft of radius were measured with a multi-layer peripheral quantitative computed tomography (pQCT). The trabecular bone and cortical bone BMD and the morphology of mid-shaft were compared. Results. Both trabecular and cortical BMD in severe AIS group was significantly lower than the control by 8.7% and 1.7% (p<0.05 for both), respectively. However, the cortical bone area of the mid-shaft did not show any differences from the normal control subjects. Discussion. This study demonstrates a systemic low BMD including the cortical bone. It is suggested that AIS girls may have disturbance in mineralization and ossification during peripubertal growth.
Original language | English |
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Title of host publication | Research into Spinal Deformities 5 |
Pages | 599-604 |
Number of pages | 6 |
Volume | 123 |
Publication status | Published - 1 Dec 2006 |
Event | 6th Biennial Meeting of the International Research Society of Spinal Deformities - Ghent, Belgium Duration: 21 Jun 2006 → 24 Jun 2006 |
Conference
Conference | 6th Biennial Meeting of the International Research Society of Spinal Deformities |
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Country | Belgium |
City | Ghent |
Period | 21/06/06 → 24/06/06 |
ASJC Scopus subject areas
- Biomedical Engineering
- Health Informatics
- Health Information Management