Low-Intensity Pulsed Ultrasound Stimulation for Bone Fractures Healing: A Review

Poornima Palanisamy; Monzurul Alam; Shuai Li; Simon K.H. Chow; Yong Ping Zheng

doi:10.1002/jum.15738

Low-Intensity Pulsed Ultrasound Stimulation for Bone Fractures Healing: A Review

Poornima Palanisamy, Monzurul Alam, Shuai Li, Simon K.H. Chow, Yong Ping Zheng

Research output: Journal article publication › Review article › Academic research › peer-review

79 Citations (Scopus)

Abstract

Low-intensity pulsed ultrasound (LIPUS) is a developing technology, which has been proven to improve fracture healing process with minimal thermal effects. This noninvasive treatment accelerates bone formation through various molecular, biological, and biomechanical interactions with tissues and cells. Although LIPUS treatment has shown beneficial effects on different bone fracture locations, only very few studies have examined its effects on deeper bones. This study provides an overview on therapeutic ultrasound for fractured bones, possible mechanisms of action, clinical evidences, current limitations, and its future prospects.

Original language	English
Pages (from-to)	547-563
Number of pages	17
Journal	Journal of Ultrasound in Medicine
Volume	41
Issue number	3
DOIs	https://doi.org/10.1002/jum.15738
Publication status	Published - Mar 2022

Keywords

bone healing
delayed unions
fresh fractures
low-intensity pulsed ultrasound
nonunions
ultrasound therapy

ASJC Scopus subject areas

Radiological and Ultrasound Technology
Radiology Nuclear Medicine and imaging

More information

10.1002/jum.15738

http://hdl.handle.net/10397/90259

Cite this

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abstract = "Low-intensity pulsed ultrasound (LIPUS) is a developing technology, which has been proven to improve fracture healing process with minimal thermal effects. This noninvasive treatment accelerates bone formation through various molecular, biological, and biomechanical interactions with tissues and cells. Although LIPUS treatment has shown beneficial effects on different bone fracture locations, only very few studies have examined its effects on deeper bones. This study provides an overview on therapeutic ultrasound for fractured bones, possible mechanisms of action, clinical evidences, current limitations, and its future prospects.",

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AU - Li, Shuai

AU - Chow, Simon K.H.

AU - Zheng, Yong Ping

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N2 - Low-intensity pulsed ultrasound (LIPUS) is a developing technology, which has been proven to improve fracture healing process with minimal thermal effects. This noninvasive treatment accelerates bone formation through various molecular, biological, and biomechanical interactions with tissues and cells. Although LIPUS treatment has shown beneficial effects on different bone fracture locations, only very few studies have examined its effects on deeper bones. This study provides an overview on therapeutic ultrasound for fractured bones, possible mechanisms of action, clinical evidences, current limitations, and its future prospects.

AB - Low-intensity pulsed ultrasound (LIPUS) is a developing technology, which has been proven to improve fracture healing process with minimal thermal effects. This noninvasive treatment accelerates bone formation through various molecular, biological, and biomechanical interactions with tissues and cells. Although LIPUS treatment has shown beneficial effects on different bone fracture locations, only very few studies have examined its effects on deeper bones. This study provides an overview on therapeutic ultrasound for fractured bones, possible mechanisms of action, clinical evidences, current limitations, and its future prospects.

KW - bone healing

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KW - fresh fractures

KW - low-intensity pulsed ultrasound

KW - nonunions

KW - ultrasound therapy

UR - https://www.scopus.com/pages/publications/85105055789

U2 - 10.1002/jum.15738

DO - 10.1002/jum.15738

M3 - Review article

AN - SCOPUS:85105055789

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Low-Intensity Pulsed Ultrasound Stimulation for Bone Fractures Healing: A Review

Abstract

Keywords

ASJC Scopus subject areas

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