Localized fluorescence excitation in opaque media by time-reversed ultrasonically encoded (TRUE) optical focusing

Yuta Suzuki; Puxiang Lai; Xiao Xu; Lihong Wang

doi:10.1117/12.2037947

Localized fluorescence excitation in opaque media by time-reversed ultrasonically encoded (TRUE) optical focusing

Yuta Suzuki, Puxiang Lai, Xiao Xu, Lihong Wang

Research output: Chapter in book / Conference proceeding › Conference article published in proceeding or book › Academic research › peer-review

Abstract

To focus light beyond one transport mean free path, time-reversed ultrasonically encoded (TRUE) optical focusing has previously been implemented by both analog and digital devices. By allowing wavefront recording with finer resolution and larger aperture, the analog scheme, which uses photorefractive materials as the phase-conjugate mirror, generates a more complete set of time-reversed optical modes than the digital scheme. Here, we report the direct visualization of localized fluorescence excitation inside a turbid medium by photorefractive time reversal. Further, we imaged fluorescent targets embedded in a turbid phantom whose thickness was four transport mean free paths.

Original language	English
Title of host publication	Photons Plus Ultrasound
Subtitle of host publication	Imaging and Sensing 2014
Publisher	SPIE
Volume	8943
ISBN (Print)	9780819498564
DOIs	https://doi.org/10.1117/12.2037947
Publication status	Published - 1 Jan 2014
Externally published	Yes
Event	Photons Plus Ultrasound: Imaging and Sensing 2014 - San Francisco, CA, United States Duration: 2 Feb 2014 → 5 Feb 2014

Conference

Conference	Photons Plus Ultrasound: Imaging and Sensing 2014
Country/Territory	United States
City	San Francisco, CA
Period	2/02/14 → 5/02/14

Keywords

Optical focusing
Optical imaging
Phase conjugation
Photorefractive material
Time reversal
Ultrasound modulation

ASJC Scopus subject areas

Atomic and Molecular Physics, and Optics
Electronic, Optical and Magnetic Materials
Biomaterials
Radiology Nuclear Medicine and imaging

More information

10.1117/12.2037947

Cite this

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title = "Localized fluorescence excitation in opaque media by time-reversed ultrasonically encoded (TRUE) optical focusing",

abstract = "To focus light beyond one transport mean free path, time-reversed ultrasonically encoded (TRUE) optical focusing has previously been implemented by both analog and digital devices. By allowing wavefront recording with finer resolution and larger aperture, the analog scheme, which uses photorefractive materials as the phase-conjugate mirror, generates a more complete set of time-reversed optical modes than the digital scheme. Here, we report the direct visualization of localized fluorescence excitation inside a turbid medium by photorefractive time reversal. Further, we imaged fluorescent targets embedded in a turbid phantom whose thickness was four transport mean free paths.",

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doi = "10.1117/12.2037947",

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Localized fluorescence excitation in opaque media by time-reversed ultrasonically encoded (TRUE) optical focusing. / Suzuki, Yuta; Lai, Puxiang; Xu, Xiao et al.
Photons Plus Ultrasound: Imaging and Sensing 2014. Vol. 8943 SPIE, 2014. 894358.

Research output: Chapter in book / Conference proceeding › Conference article published in proceeding or book › Academic research › peer-review

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N2 - To focus light beyond one transport mean free path, time-reversed ultrasonically encoded (TRUE) optical focusing has previously been implemented by both analog and digital devices. By allowing wavefront recording with finer resolution and larger aperture, the analog scheme, which uses photorefractive materials as the phase-conjugate mirror, generates a more complete set of time-reversed optical modes than the digital scheme. Here, we report the direct visualization of localized fluorescence excitation inside a turbid medium by photorefractive time reversal. Further, we imaged fluorescent targets embedded in a turbid phantom whose thickness was four transport mean free paths.

AB - To focus light beyond one transport mean free path, time-reversed ultrasonically encoded (TRUE) optical focusing has previously been implemented by both analog and digital devices. By allowing wavefront recording with finer resolution and larger aperture, the analog scheme, which uses photorefractive materials as the phase-conjugate mirror, generates a more complete set of time-reversed optical modes than the digital scheme. Here, we report the direct visualization of localized fluorescence excitation inside a turbid medium by photorefractive time reversal. Further, we imaged fluorescent targets embedded in a turbid phantom whose thickness was four transport mean free paths.

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KW - Optical imaging

KW - Phase conjugation

KW - Photorefractive material

KW - Time reversal

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M3 - Conference article published in proceeding or book

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BT - Photons Plus Ultrasound

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T2 - Photons Plus Ultrasound: Imaging and Sensing 2014

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Localized fluorescence excitation in opaque media by time-reversed ultrasonically encoded (TRUE) optical focusing

Abstract

Conference

Keywords

ASJC Scopus subject areas

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