Localized fluorescence excitation in opaque media by time-reversed ultrasonically encoded (TRUE) optical focusing

Yuta Suzuki, Puxiang Lai, Xiao Xu, Lihong Wang

Research output: Chapter in book / Conference proceedingConference article published in proceeding or bookAcademic researchpeer-review


To focus light beyond one transport mean free path, time-reversed ultrasonically encoded (TRUE) optical focusing has previously been implemented by both analog and digital devices. By allowing wavefront recording with finer resolution and larger aperture, the analog scheme, which uses photorefractive materials as the phase-conjugate mirror, generates a more complete set of time-reversed optical modes than the digital scheme. Here, we report the direct visualization of localized fluorescence excitation inside a turbid medium by photorefractive time reversal. Further, we imaged fluorescent targets embedded in a turbid phantom whose thickness was four transport mean free paths.
Original languageEnglish
Title of host publicationPhotons Plus Ultrasound
Subtitle of host publicationImaging and Sensing 2014
ISBN (Print)9780819498564
Publication statusPublished - 1 Jan 2014
Externally publishedYes
EventPhotons Plus Ultrasound: Imaging and Sensing 2014 - San Francisco, CA, United States
Duration: 2 Feb 20145 Feb 2014


ConferencePhotons Plus Ultrasound: Imaging and Sensing 2014
Country/TerritoryUnited States
CitySan Francisco, CA


  • Optical focusing
  • Optical imaging
  • Phase conjugation
  • Photorefractive material
  • Time reversal
  • Ultrasound modulation

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics
  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

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