Laser-induced thermal bubbles for microfluidic applications

Kai Zhang, Aoqun Jian, Xuming Zhang, Yu Wang, Zhaohui Li, Hwa Yaw Tam

Research output: Journal article publicationJournal articleAcademic researchpeer-review

96 Citations (Scopus)

Abstract

We present a unique bubble generation technique in microfluidic chips using continuous-wave laser-induced heat and demonstrate its application by creating micro-valves and micro-pumps. In this work, efficient generation of thermal bubbles of controllable sizes has been achieved using different geometries of chromium pads immersed in various types of fluid. Effective blocking of microfluidic channels (cross-section 500 × 40 μm2) and direct pumping of fluid at a flow rate of 7.2-28.8 μl h-1with selectable direction have also been demonstrated. A particular advantage of this technique is that it allows the generation of bubbles at almost any location in the microchannel and thus enables microfluidic control at any point of interest. It can be readily integrated into lab-on-a-chip systems to improve functionality.
Original languageEnglish
Pages (from-to)1389-1395
Number of pages7
JournalLab on a Chip
Volume11
Issue number7
DOIs
Publication statusPublished - 7 Apr 2011

ASJC Scopus subject areas

  • Bioengineering
  • Biochemistry
  • Chemistry(all)
  • Biomedical Engineering

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