Laser in situ keratomileusis induced corneal perforation and recurrent corneal epithelial ingrowth

Quan Liu, Ming Gong Xiang, Qi Chen Jia, Bin Yang, Jian Ge, Chi Ho To

Research output: Journal article publicationJournal articleAcademic researchpeer-review

7 Citations (Scopus)


We report a rare complication of recurrent corneal epithelial cell ingrowth after corneal perforation induced by laser in situ keratomileusis. A corneal flap was made uneventfully with an automatic SCMD microkeratome (Howard Instruments, Inc.). During laser ablation, instead of random burning over the stromal bed, repeated ablation at a single location occurred because of a machine malfunction, resulting in corneal perforation. The flap was replaced and sutured to prevent leakage of aqueous humor. As the cornea healed, the patient's vision was compromised by scar formation, high irregular astigmatism, and epithelial ingrowth. The flap was reopened, and the epithelial cells were removed by thoroughly scraping the flap and stromal bed. However, corneal epithelial ingrowth recurred within a week. The recurrent and progressive epithelial ingrowth further decreased vision, and penetrating keratoplasty was recommended.
Original languageEnglish
Pages (from-to)857-859
Number of pages3
JournalJournal of Cataract and Refractive Surgery
Issue number4
Publication statusPublished - 1 Apr 2005

ASJC Scopus subject areas

  • Surgery
  • Ophthalmology
  • Sensory Systems

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