Label-free DNA biosensor based on cladding-etched thin-core fiber modal interferometer

Guiying Ma; Aping Zhang; Guofeng Yan; Yinbing Bai; Yichuan Hu; Xuesong Ye

doi:10.1117/12.974989

Label-free DNA biosensor based on cladding-etched thin-core fiber modal interferometer

Guiying Ma
, Aping Zhang
, Guofeng Yan
, Yinbing Bai
, Yichuan Hu
, Xuesong Ye

Research output: Chapter in book / Conference proceeding › Conference article published in proceeding or book › Academic research › peer-review

4 Citations (Scopus)

Abstract

The fabrication and characterization of a highly sensitive DNA biosensor based on thin-core fiber modal interferometer (TCFMI) are presented. The TCFMI is made by using a thin-core fiber (TCF) with core diameter of ∼3.0 μm and etched by using Hydrofluoric (HF) acid solution for sensitivity enhancement. A thin layer of polymer (PLL, poly-L-lysine) was coated on the sensor surface and experimentally demonstrated for the detection of hybridization of deoxyribonucleic acid (DNA).

Original language	English
Title of host publication	22nd International Conference on Optical Fiber Sensors
Volume	8421
DOIs	https://doi.org/10.1117/12.974989
Publication status	Published - 1 Dec 2012
Externally published	Yes
Event	22nd International Conference on Optical Fiber Sensors - Beijing, China Duration: 15 Oct 2012 → 19 Oct 2012

Conference

Conference	22nd International Conference on Optical Fiber Sensors
Country/Territory	China
City	Beijing
Period	15/10/12 → 19/10/12

Keywords

DNA sensor
Label-free biosensor
Optical fiber interferometer

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Condensed Matter Physics
Computer Science Applications
Applied Mathematics
Electrical and Electronic Engineering

More information

10.1117/12.974989

Cite this

@inproceedings{a556c1a61c4f49c2a1d9c3c020cb0774,

title = "Label-free DNA biosensor based on cladding-etched thin-core fiber modal interferometer",

abstract = "The fabrication and characterization of a highly sensitive DNA biosensor based on thin-core fiber modal interferometer (TCFMI) are presented. The TCFMI is made by using a thin-core fiber (TCF) with core diameter of ∼3.0 μm and etched by using Hydrofluoric (HF) acid solution for sensitivity enhancement. A thin layer of polymer (PLL, poly-L-lysine) was coated on the sensor surface and experimentally demonstrated for the detection of hybridization of deoxyribonucleic acid (DNA).",

keywords = "DNA sensor, Label-free biosensor, Optical fiber interferometer",

author = "Guiying Ma and Aping Zhang and Guofeng Yan and Yinbing Bai and Yichuan Hu and Xuesong Ye",

year = "2012",

month = dec,

day = "1",

doi = "10.1117/12.974989",

language = "English",

isbn = "9780819491039",

volume = "8421",

booktitle = "22nd International Conference on Optical Fiber Sensors",

note = "22nd International Conference on Optical Fiber Sensors ; Conference date: 15-10-2012 Through 19-10-2012",

}

TY - GEN

T1 - Label-free DNA biosensor based on cladding-etched thin-core fiber modal interferometer

AU - Ma, Guiying

AU - Zhang, Aping

AU - Yan, Guofeng

AU - Bai, Yinbing

AU - Hu, Yichuan

AU - Ye, Xuesong

PY - 2012/12/1

Y1 - 2012/12/1

N2 - The fabrication and characterization of a highly sensitive DNA biosensor based on thin-core fiber modal interferometer (TCFMI) are presented. The TCFMI is made by using a thin-core fiber (TCF) with core diameter of ∼3.0 μm and etched by using Hydrofluoric (HF) acid solution for sensitivity enhancement. A thin layer of polymer (PLL, poly-L-lysine) was coated on the sensor surface and experimentally demonstrated for the detection of hybridization of deoxyribonucleic acid (DNA).

AB - The fabrication and characterization of a highly sensitive DNA biosensor based on thin-core fiber modal interferometer (TCFMI) are presented. The TCFMI is made by using a thin-core fiber (TCF) with core diameter of ∼3.0 μm and etched by using Hydrofluoric (HF) acid solution for sensitivity enhancement. A thin layer of polymer (PLL, poly-L-lysine) was coated on the sensor surface and experimentally demonstrated for the detection of hybridization of deoxyribonucleic acid (DNA).

KW - DNA sensor

KW - Label-free biosensor

KW - Optical fiber interferometer

UR - https://www.scopus.com/pages/publications/84875616889

U2 - 10.1117/12.974989

DO - 10.1117/12.974989

M3 - Conference article published in proceeding or book

SN - 9780819491039

VL - 8421

BT - 22nd International Conference on Optical Fiber Sensors

T2 - 22nd International Conference on Optical Fiber Sensors

Y2 - 15 October 2012 through 19 October 2012

ER -

Label-free DNA biosensor based on cladding-etched thin-core fiber modal interferometer

Abstract

Conference

Keywords

ASJC Scopus subject areas

More information

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