Label-free DNA biosensor based on cladding-etched thin-core fiber modal interferometer

Guiying Ma, Aping Zhang, Guofeng Yan, Yinbing Bai, Yichuan Hu, Xuesong Ye

Research output: Chapter in book / Conference proceedingConference article published in proceeding or bookAcademic researchpeer-review

3 Citations (Scopus)

Abstract

The fabrication and characterization of a highly sensitive DNA biosensor based on thin-core fiber modal interferometer (TCFMI) are presented. The TCFMI is made by using a thin-core fiber (TCF) with core diameter of ∼3.0 μm and etched by using Hydrofluoric (HF) acid solution for sensitivity enhancement. A thin layer of polymer (PLL, poly-L-lysine) was coated on the sensor surface and experimentally demonstrated for the detection of hybridization of deoxyribonucleic acid (DNA).
Original languageEnglish
Title of host publication22nd International Conference on Optical Fiber Sensors
Volume8421
DOIs
Publication statusPublished - 1 Dec 2012
Externally publishedYes
Event22nd International Conference on Optical Fiber Sensors - Beijing, China
Duration: 15 Oct 201219 Oct 2012

Conference

Conference22nd International Conference on Optical Fiber Sensors
CountryChina
CityBeijing
Period15/10/1219/10/12

Keywords

  • DNA sensor
  • Label-free biosensor
  • Optical fiber interferometer

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering

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