The design process comprises the Conceptual Phase, the Embodiment Phase and the Detail Design Phase in which commercial PLM/CAD systems mainly support the latter ones. This situation causes the discontinuity in the overall design information flow: Customer Needs (CNs) - Functional Requirements (FRs) - Design Parameters (DPs) - Key Characteristics (KCs) - Geometric Parameters (GPs). There is also a lack of knowledge reuse in routine design process, resulting in large cost-waste of the overall design process. Aiming to enhance the continuity of the design information flow and facilitate the knowledge reuse, this paper makes use of a knowledge-based framework to integrate conceptual design tools: Quality Function Deployment (QFD), Axiomatic Design (AD), Failure Mode and Effects Analysis (FMEA) and the MOKA methodology into CATIA v5 system. A knowledge-based application (KBA) on the large aircraft y-bolt component design is presented as a case study to validate the proposed framework. The result shows how this novel integrated framework and KBA system could benefit designers in a practical way.