Abstract
Autophagy is an important catabolic process in which cells digest and recycle their own cytoplasmic contents for maintaining cellular homeostasis. Interestingly, autophagy could play both pro-death and pro-survival roles in influencing the development of cancer via various signal pathways. As radiotherapy is one of the main treatment modalities for cancer, we reviewed the effect of autophagy modulations on radiosensitivity and radiotherapy efficacy in various cancer types. The future development of autophagy modifications for improving radiotherapy efficacy and cancer prognosis will also be discussed.
| Original language | English |
|---|---|
| Article number | 57 |
| Journal | Radiation Oncology |
| Volume | 12 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - 21 Mar 2017 |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
-
SDG 3 Good Health and Well-being
Keywords
- Autophagy
- Cancer Cell lines
- Radiosensitivity
- Radiotherapy
- Radiotherapy efficacy
- Signalling pathway
ASJC Scopus subject areas
- Oncology
- Radiology Nuclear Medicine and imaging
Fingerprint
Dive into the research topics of 'Influence of autophagy on the efficacy of radiotherapy'. Together they form a unique fingerprint.Cite this
- APA
- Author
- BIBTEX
- Harvard
- Standard
- RIS
- Vancouver