IncHI2 plasmids are the key vectors responsible for oqxAB transmission among Salmonella species

Marcus Ho Yin Wong, Edward Wai Chi Chan, Liqi Xie, Ruichao Li, Sheng Chen

Research output: Journal article publicationJournal articleAcademic researchpeer-review

18 Citations (Scopus)

Abstract

This study reported and analyzed the complete sequences of two oqxAB-bearing IncHI2 plasmids harbored by a clinical Salmonella enterica serovar Typhimurium strain and an S. Indiana strain of animal origin, respectively. In particular, pA3T recovered from S. Indiana comprised the resistance determinants oqxAB, aac(6′)Ib-cr, fosA3, and blaCTX-M-14. Further genetic screening of 63 oqxAB-positive Salmonella isolates revealed that the majority carried IncHI2 plasmids, confirming that such plasmids play a pivotal role in dissemination of oqxAB in Salmonella spp.
Original languageEnglish
Pages (from-to)6911-6915
Number of pages5
JournalAntimicrobial Agents and Chemotherapy
Volume60
Issue number11
DOIs
Publication statusPublished - 1 Nov 2016

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)
  • Infectious Diseases

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