@inproceedings{b108cf3e9ee2409a9a6dda505f9efc0d,
title = "In vivo diffusion tensor imaging of chronic spinal cord compression in rat model",
abstract = "Chronic spinal cord compression induced cervical myelopathy is a comon cause of spinal cord dysfunction. The exact mechanisms of underlying progressive cell death remain to be elucidated. In this study, in vivo diffusion tensor imaging (DTI) has been applied to investigate the microstructural changes of white matter (WM) in this neurodegenerative disease. Compared with conventional MRI techniques, DTI is believed to be more specific to pathological changes. Radial diffusivity (λ⊥) is higher in the ipilesional region, suggesting demyelination or axonal degradation may occur after prolonged compression. Near the epicenter of lesion, axial diffusivity (λ∥) is lower. Also, caudal-rostral asymmetry has been observed in λ∥. Feasibility of using DTI to detect microstructural changes in chronic disease has been demonstrated.",
keywords = "Axial diffusivity, Cervical myelopathy, DTI, MRI, Radial diffusivity, Spinal cord compression",
author = "Cheung, {Matthew M.} and Li, {Darrell T.H.} and Hui, {Edward S.} and Shujuan Fan and Ding, {Abby Y.} and Yong Hu and Wu, {Ed X.}",
note = "Copyright: Copyright 2012 Elsevier B.V., All rights reserved.; 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009 ; Conference date: 02-09-2009 Through 06-09-2009",
year = "2009",
month = nov,
doi = "10.1109/IEMBS.2009.5333389",
language = "English",
isbn = "9781424432967",
series = "Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009",
pages = "2715--2718",
booktitle = "Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society",
}