In vivo and real-time monitoring of secondary metabolites of living organisms by mass spectrometry

Bin Hu, Lei Wang, Wen Cai Ye, Zhongping Yao

Research output: Journal article publicationJournal articleAcademic researchpeer-review

38 Citations (Scopus)


Secondary metabolites are compounds that are important for the survival and propagation of animals and plants. Our current understanding on the roles and secretion mechanism of secondary metabolites is limited by the existing techniques that typically cannot provide transient and dynamic information about the metabolic processes. In this manuscript, by detecting venoms secreted by living scorpion and toad upon attack and variation of alkaloids in living Catharanthus roseus upon stimulation, which represent three different sampling methods for living organisms, we demonstrated that in vivo and real-time monitoring of secondary metabolites released from living animals and plants could be readily achieved by using field-induced direct ionization mass spectrometry.
Original languageEnglish
Article number2104
JournalScientific Reports
Publication statusPublished - 18 Jul 2013

ASJC Scopus subject areas

  • General

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