In vitro degradation and subsequent biomechanical changes of braided biodegradable conduits for peripheral nerve regeneration

Guo Hua Liu; Hong Hu; Pei Hua Zhang; Wen Zu Wang

In vitro degradation and subsequent biomechanical changes of braided biodegradable conduits for peripheral nerve regeneration

Guo Hua Liu, Hong Hu, Pei Hua Zhang, Wen Zu Wang

Research output: Chapter in book / Conference proceeding › Conference article published in proceeding or book › Academic research › peer-review

Abstract

A new kind of the biodegradable poly (glycolide-co-lactide acid) (PGLA) conduits for peripheral nerve regeneration were produced by braiding technology and soaking process. The in vitro degradation was simulated by immerging the conduits in a phosphate buffer saline (PBS) solution with pH 7.4 at 37°C. The variations of the mass and radial compressive properties during in vitro degradation were investigated. The influences of the composition of the polymeric materials and the braided structures were discussed. The results have shown that conduits produced with triaxial braided structure and PGLA (90:10) have stable biomechanical performance with feasible degradation rate, which can be more effective for nerve regeneration and repair and may lead to clinical application.

Original language	English
Title of host publication	"New Century, New Materials and New Life" - Proceedings of 2005 International Conference on Advanced Fibers and Polymer Materials, ICAFPM 2005
Publisher	China Press
Pages	979-982
Number of pages	4
Volume	2
ISBN (Print)	7502577173, 9787502577179
Publication status	Published - 1 Jan 2005
Externally published	Yes
Event	2005 International Conference on Advanced Fibers and Polymer Materials, ICAFPM 2005 - Shanghai, China Duration: 19 Oct 2005 → 21 Oct 2005

Conference

Conference	2005 International Conference on Advanced Fibers and Polymer Materials, ICAFPM 2005
Country/Territory	China
City	Shanghai
Period	19/10/05 → 21/10/05

ASJC Scopus subject areas

Polymers and Plastics
Biomaterials

Cite this

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title = "In vitro degradation and subsequent biomechanical changes of braided biodegradable conduits for peripheral nerve regeneration",

abstract = "A new kind of the biodegradable poly (glycolide-co-lactide acid) (PGLA) conduits for peripheral nerve regeneration were produced by braiding technology and soaking process. The in vitro degradation was simulated by immerging the conduits in a phosphate buffer saline (PBS) solution with pH 7.4 at 37°C. The variations of the mass and radial compressive properties during in vitro degradation were investigated. The influences of the composition of the polymeric materials and the braided structures were discussed. The results have shown that conduits produced with triaxial braided structure and PGLA (90:10) have stable biomechanical performance with feasible degradation rate, which can be more effective for nerve regeneration and repair and may lead to clinical application.",

author = "Liu, {Guo Hua} and Hong Hu and Zhang, {Pei Hua} and Wang, {Wen Zu}",

year = "2005",

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language = "English",

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volume = "2",

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booktitle = "{"}New Century, New Materials and New Life{"} - Proceedings of 2005 International Conference on Advanced Fibers and Polymer Materials, ICAFPM 2005",

publisher = "China Press",

note = "2005 International Conference on Advanced Fibers and Polymer Materials, ICAFPM 2005 ; Conference date: 19-10-2005 Through 21-10-2005",

}

Liu, GH, Hu, H, Zhang, PH & Wang, WZ 2005, In vitro degradation and subsequent biomechanical changes of braided biodegradable conduits for peripheral nerve regeneration. in "New Century, New Materials and New Life" - Proceedings of 2005 International Conference on Advanced Fibers and Polymer Materials, ICAFPM 2005. vol. 2, China Press, pp. 979-982, 2005 International Conference on Advanced Fibers and Polymer Materials, ICAFPM 2005, Shanghai, China, 19/10/05.

In vitro degradation and subsequent biomechanical changes of braided biodegradable conduits for peripheral nerve regeneration. / Liu, Guo Hua; Hu, Hong; Zhang, Pei Hua et al.
"New Century, New Materials and New Life" - Proceedings of 2005 International Conference on Advanced Fibers and Polymer Materials, ICAFPM 2005. Vol. 2 China Press, 2005. p. 979-982.

Research output: Chapter in book / Conference proceeding › Conference article published in proceeding or book › Academic research › peer-review

TY - GEN

T1 - In vitro degradation and subsequent biomechanical changes of braided biodegradable conduits for peripheral nerve regeneration

AU - Liu, Guo Hua

AU - Hu, Hong

AU - Zhang, Pei Hua

AU - Wang, Wen Zu

PY - 2005/1/1

Y1 - 2005/1/1

N2 - A new kind of the biodegradable poly (glycolide-co-lactide acid) (PGLA) conduits for peripheral nerve regeneration were produced by braiding technology and soaking process. The in vitro degradation was simulated by immerging the conduits in a phosphate buffer saline (PBS) solution with pH 7.4 at 37°C. The variations of the mass and radial compressive properties during in vitro degradation were investigated. The influences of the composition of the polymeric materials and the braided structures were discussed. The results have shown that conduits produced with triaxial braided structure and PGLA (90:10) have stable biomechanical performance with feasible degradation rate, which can be more effective for nerve regeneration and repair and may lead to clinical application.

AB - A new kind of the biodegradable poly (glycolide-co-lactide acid) (PGLA) conduits for peripheral nerve regeneration were produced by braiding technology and soaking process. The in vitro degradation was simulated by immerging the conduits in a phosphate buffer saline (PBS) solution with pH 7.4 at 37°C. The variations of the mass and radial compressive properties during in vitro degradation were investigated. The influences of the composition of the polymeric materials and the braided structures were discussed. The results have shown that conduits produced with triaxial braided structure and PGLA (90:10) have stable biomechanical performance with feasible degradation rate, which can be more effective for nerve regeneration and repair and may lead to clinical application.

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M3 - Conference article published in proceeding or book

SN - 7502577173

SN - 9787502577179

VL - 2

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EP - 982

BT - "New Century, New Materials and New Life" - Proceedings of 2005 International Conference on Advanced Fibers and Polymer Materials, ICAFPM 2005

PB - China Press

T2 - 2005 International Conference on Advanced Fibers and Polymer Materials, ICAFPM 2005

Y2 - 19 October 2005 through 21 October 2005

ER -

In vitro degradation and subsequent biomechanical changes of braided biodegradable conduits for peripheral nerve regeneration

Abstract

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ASJC Scopus subject areas

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