Immobilization of small proteins in carbon nanotubes: High-resolution transmission electron microscopy study and catalytic activity

S. C. Tsang, J. J. Davis, Malcolm L.H. Green, H. Allen O. Hill, Yun Chung Leung, Peter J. Sadler

Research output: Journal article publicationJournal articleAcademic researchpeer-review

131 Citations (Scopus)

Abstract

The morphologies of the small proteins Zn2Cd5- metallothionein, cytochrome c3 and β-lactamase I immobilized inside carbon nanotubes have been studied by high-resolution transmission electron microscopy (HRTEM); single protein molecules and their associated forms were clearly observed inside the central cavity and a significant amount remained catalytically active indicating that no drastic conformational change had taken place.
Original languageEnglish
Pages (from-to)1803-1804
Number of pages2
JournalJournal of the Chemical Society, Chemical Communications
Issue number17
DOIs
Publication statusPublished - 1 Dec 1995
Externally publishedYes

ASJC Scopus subject areas

  • Molecular Medicine

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