Immersion refractometry analysis of living cells in microfluidic cell culture chip

X. Zhang, R. Chua, P. H. Yap, W. Z. Song, A. Q. Liu

Research output: Chapter in book / Conference proceedingConference article published in proceeding or bookAcademic researchpeer-review

Abstract

This paper reports a method for measuring the refractive index (RI) of living cells using immersion refractometry integrated with microfluidics. Theoretically, the RI of the cells can be determined to an accuracy of 0.0001. This method features high speed, high accuracy, less damage to cells, ultra integration and real time measurement during long-term cell culture, making it promising for many applications, for example, real-time monitoring of cells.

Original languageEnglish
Title of host publicationProceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007
EditorsJean-Louis Viovy, Patrick Tabeling, Stephanie Descroix, Laurent Malaquin
PublisherChemical and Biological Microsystems Society
Pages461-463
Number of pages3
ISBN (Electronic)9780979806407
Publication statusPublished - Oct 2007
Externally publishedYes
Event11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007 - Paris, France
Duration: 7 Oct 200711 Oct 2007

Publication series

NameProceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007

Conference

Conference11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007
Country/TerritoryFrance
CityParis
Period7/10/0711/10/07

Keywords

  • Cell culture
  • Immersion refractometry
  • Lab on a chip
  • Living cell

ASJC Scopus subject areas

  • Chemical Engineering (miscellaneous)
  • Bioengineering

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