Hydro(trispyrazolyl)borato-ruthenium(II) diphosphinoamino complex-catalyzed addition of β-diketones to 1-alkynes and anti-markovnikov addition of secondary amines to aromatic 1-alkynes

Hung Wai Cheung, Chau Ming So, Kwok Hung Pun, Zhongyuan Zhou, Chak Po Lau

Research output: Journal article publicationJournal articleAcademic researchpeer-review

32 Citations (Scopus)

Abstract

The hydro(trispyrazolyl)borato-ruthenium(II) diphosphinoamino complex TpRu[4-CF3C6H4N(PPh2)2](OTf) (I) [Tp=hydro(trispyrazolyl)borate] catalyzes the Markovnikov addition of β-diketones to unactivated 1-alkynes in good to excellent yields. The reaction proceeds under solvent-free and additive-free conditions and the catalyst loading can be reduced down to 0.4amol%. Complex I (1amol%) also catalyzes the addition of secondary amines to aromatic terminal alkynes, unusual anti-Markovnikov products are exclusively formed. KGaA, Weinheim.
Original languageEnglish
Pages (from-to)411-425
Number of pages15
JournalAdvanced Synthesis and Catalysis
Volume353
Issue number2-3
DOIs
Publication statusPublished - 11 Feb 2011

Keywords

  • β-diketones
  • 1-alkynes
  • addition reaction
  • ruthenium
  • secondary amines

ASJC Scopus subject areas

  • Catalysis
  • Organic Chemistry

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