Highly enantioselective hydrogenation of enamides catalyzed by rhodium-monodentate phosphoramidite complex derived from H8-BINOL

Xingshu Li; Xian Jia; Gui Lu; Terry T.L. Au-Yeung; Kim Hung Lam; Wai Hung Lo; Albert S.C. Chan

doi:10.1016/j.tetasy.2003.07.005

Highly enantioselective hydrogenation of enamides catalyzed by rhodium-monodentate phosphoramidite complex derived from H₈-BINOL

Xingshu Li
, Xian Jia
, Gui Lu
, Terry T.L. Au-Yeung
, Kim Hung Lam
, Wai Hung Lo
, Albert S.C. Chan

Research output: Journal article publication › Journal article › Academic research › peer-review

38 Citations (Scopus)

Abstract

A series of monodentate phosphoramidite ligands derived from H8-BINOL have been synthesized. The ligands are used in the Rh-catalyzed asymmetric hydrogenation of enamides to give the acetamides in up to 99% ee.

Original language	English
Pages (from-to)	2687-2691
Number of pages	5
Journal	Tetrahedron Asymmetry
Volume	14
Issue number	18
DOIs	https://doi.org/10.1016/j.tetasy.2003.07.005
Publication status	Published - 19 Sept 2003

ASJC Scopus subject areas

Catalysis
Physical and Theoretical Chemistry
Organic Chemistry
Inorganic Chemistry

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10.1016/j.tetasy.2003.07.005

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title = "Highly enantioselective hydrogenation of enamides catalyzed by rhodium-monodentate phosphoramidite complex derived from H8-BINOL",

abstract = "A series of monodentate phosphoramidite ligands derived from H8-BINOL have been synthesized. The ligands are used in the Rh-catalyzed asymmetric hydrogenation of enamides to give the acetamides in up to 99\% ee.",

author = "Xingshu Li and Xian Jia and Gui Lu and Au-Yeung, \{Terry T.L.\} and Lam, \{Kim Hung\} and Lo, \{Wai Hung\} and Chan, \{Albert S.C.\}",

year = "2003",

month = sep,

day = "19",

doi = "10.1016/j.tetasy.2003.07.005",

language = "English",

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journal = "Tetrahedron Asymmetry",

issn = "0957-4166",

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T1 - Highly enantioselective hydrogenation of enamides catalyzed by rhodium-monodentate phosphoramidite complex derived from H8-BINOL

AU - Li, Xingshu

AU - Jia, Xian

AU - Lu, Gui

AU - Au-Yeung, Terry T.L.

AU - Lam, Kim Hung

AU - Lo, Wai Hung

AU - Chan, Albert S.C.

PY - 2003/9/19

Y1 - 2003/9/19

N2 - A series of monodentate phosphoramidite ligands derived from H8-BINOL have been synthesized. The ligands are used in the Rh-catalyzed asymmetric hydrogenation of enamides to give the acetamides in up to 99% ee.

AB - A series of monodentate phosphoramidite ligands derived from H8-BINOL have been synthesized. The ligands are used in the Rh-catalyzed asymmetric hydrogenation of enamides to give the acetamides in up to 99% ee.

UR - https://www.scopus.com/pages/publications/1842536158

U2 - 10.1016/j.tetasy.2003.07.005

DO - 10.1016/j.tetasy.2003.07.005

M3 - Journal article

SN - 0957-4166

VL - 14

SP - 2687

EP - 2691

JO - Tetrahedron Asymmetry

JF - Tetrahedron Asymmetry

IS - 18

ER -

Highly enantioselective hydrogenation of enamides catalyzed by rhodium-monodentate phosphoramidite complex derived from H₈-BINOL

Abstract

ASJC Scopus subject areas

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