Highly diastereo- and enantioselective intramolecular amidation of saturated C-H bonds catalyzed by ruthenium porphyrins

Jiang Lin Liang, Shi Xue Yuan, Jie Sheng Huang, Wing Yiu Yu, Chi Ming Che

Research output: Journal article publicationJournal articleAcademic researchpeer-review

243 Citations (Scopus)

Abstract

Virtually complete diastereoselectivity is observed in the intramolecular amidation of saturated C-H bonds, catalyzed by the ruthenium porphyrin catalyst 1 or 2. Reactions of sulfamate esters with PhI(OAc)2 in the presence of 1 or 2 afforded cyclic sulfamidates in up to 87% ee.
Original languageEnglish
Pages (from-to)3465-3468
Number of pages4
JournalAngewandte Chemie - International Edition
Volume41
Issue number18
DOIs
Publication statusPublished - 16 Sep 2002
Externally publishedYes

Keywords

  • Asymmetric catalysis
  • Cyclization
  • Porphyrinoids
  • Ruthenium
  • Sulfamidates

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)

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