Abstract
Time-reversed ultrasonically encoded (TRUE) optical focusing is an emerging technique that focuses light deep into scattering media by phase-conjugating ultrasonically encoded diffuse light. In previous work, the speed of TRUE focusing was limited to no faster than 1 Hz by the response time of the photorefractive phase conjugate mirror, or the data acquisition and streaming speed of the digital camera; photorefractive-crystal-based TRUE focusing was also limited to the visible spectral range. These time-consuming schemes prevent this technique from being applied in vivo, since living biological tissue has a speckle decorrelation time on the order of a millisecond. In this work, using a Tedoped Sn2P2S6 photorefractive crystal at a near-infrared wavelength of 793 nm, we achieved TRUE focusing inside dynamic scattering media having a speckle decorrelation time as short as 7.7 ms. As the achieved speed approaches the tissue decorrelation rate, this work is an important step forward toward in vivo applications of TRUE focusing in deep tissue imaging, photodynamic therapy, and optical manipulation.
Original language | English |
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Title of host publication | Photons Plus Ultrasound |
Subtitle of host publication | Imaging and Sensing 2014 |
Publisher | SPIE |
Volume | 8943 |
ISBN (Print) | 9780819498564 |
DOIs | |
Publication status | Published - 1 Jan 2014 |
Externally published | Yes |
Event | Photons Plus Ultrasound: Imaging and Sensing 2014 - San Francisco, CA, United States Duration: 2 Feb 2014 → 5 Feb 2014 |
Conference
Conference | Photons Plus Ultrasound: Imaging and Sensing 2014 |
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Country | United States |
City | San Francisco, CA |
Period | 2/02/14 → 5/02/14 |
Keywords
- Light scattering
- Optical focusing
- Optical phase conjugation
- Optical time reversal
- Time-Reversed Ultrasonically Encoded (TRUE) optical focusing
- Turbid media
ASJC Scopus subject areas
- Atomic and Molecular Physics, and Optics
- Electronic, Optical and Magnetic Materials
- Biomaterials
- Radiology Nuclear Medicine and imaging