@inproceedings{1f487a0de40f461393f49ed8129dedc7,
title = "Hepatocyte co-culture in alginate hydrogel for anti-cancer drug analysis",
abstract = "This paper presents the formation of double-layer cellular tumor spheroid for the co-culture of hepatocyte (HepG2 cancer liver cell and LO2 normal liver cell) using alginate hydrogel. With the microfluidic chip, double-layer cellular tumor spheroid can be formed by the hydrogel droplet to mimic the in vivo environment in which the cancer cell is surrounded by normal cell. A microchip with concentration gradient generation and tumor spheroid trapping site is designed for anti-cancer drug analysis.",
keywords = "Co-culture, Drug analysis, Hepatocyte, Hydrogel",
author = "Chin, {L. K.} and Luo, {K. Q.} and Liu, {A. Q.}",
year = "2011",
month = oct,
language = "English",
isbn = "9781618395955",
series = "15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011",
pages = "1499--1501",
booktitle = "15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011",
note = "15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011 ; Conference date: 02-10-2011 Through 06-10-2011",
}