Gold-mediated bifunctional modification of oligosaccharides via a three-component coupling reaction

Karen Ka Yan Kung; Gai Li Li; Lan Zou; Hiu Chi Chong; Yun Chung Leung; Ka Hing Wong; Vanessa Kar Yan Lo; Chi Ming Che; Man Kin Wong

doi:10.1039/c1ob06429k

Gold-mediated bifunctional modification of oligosaccharides via a three-component coupling reaction

Karen Ka Yan Kung
, Gai Li Li
, Lan Zou
, Hiu Chi Chong
, Yun Chung Leung
, Ka Hing Wong
, Vanessa Kar Yan Lo
, Chi Ming Che
, Man Kin Wong

Research output: Journal article publication › Journal article › Academic research › peer-review

44 Citations (Scopus)

Abstract

An efficient modular approach for single-site incorporation of two independent functionalities (amines and alkynes) into aldehyde-containing oligosaccharides concurrently by using a one-pot gold-mediated three-component coupling reaction in aqueous medium under mild conditions has been developed.

Original language	English
Pages (from-to)	925-930
Number of pages	6
Journal	Organic and Biomolecular Chemistry
Volume	10
Issue number	5
DOIs	https://doi.org/10.1039/c1ob06429k
Publication status	Published - 7 Feb 2012

ASJC Scopus subject areas

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry

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10.1039/c1ob06429k

Cite this

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title = "Gold-mediated bifunctional modification of oligosaccharides via a three-component coupling reaction",

abstract = "An efficient modular approach for single-site incorporation of two independent functionalities (amines and alkynes) into aldehyde-containing oligosaccharides concurrently by using a one-pot gold-mediated three-component coupling reaction in aqueous medium under mild conditions has been developed.",

author = "Kung, \{Karen Ka Yan\} and Li, \{Gai Li\} and Lan Zou and Chong, \{Hiu Chi\} and Leung, \{Yun Chung\} and Wong, \{Ka Hing\} and Lo, \{Vanessa Kar Yan\} and Che, \{Chi Ming\} and Wong, \{Man Kin\}",

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AU - Kung, Karen Ka Yan

AU - Li, Gai Li

AU - Zou, Lan

AU - Chong, Hiu Chi

AU - Leung, Yun Chung

AU - Wong, Ka Hing

AU - Lo, Vanessa Kar Yan

AU - Che, Chi Ming

AU - Wong, Man Kin

PY - 2012/2/7

Y1 - 2012/2/7

N2 - An efficient modular approach for single-site incorporation of two independent functionalities (amines and alkynes) into aldehyde-containing oligosaccharides concurrently by using a one-pot gold-mediated three-component coupling reaction in aqueous medium under mild conditions has been developed.

AB - An efficient modular approach for single-site incorporation of two independent functionalities (amines and alkynes) into aldehyde-containing oligosaccharides concurrently by using a one-pot gold-mediated three-component coupling reaction in aqueous medium under mild conditions has been developed.

UR - https://www.scopus.com/pages/publications/84863011489

U2 - 10.1039/c1ob06429k

DO - 10.1039/c1ob06429k

M3 - Journal article

C2 - 22076205

SN - 1477-0520

VL - 10

SP - 925

EP - 930

JO - Organic and Biomolecular Chemistry

JF - Organic and Biomolecular Chemistry

IS - 5

ER -

Gold-mediated bifunctional modification of oligosaccharides via a three-component coupling reaction

Abstract

ASJC Scopus subject areas

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