Gold-mediated bifunctional modification of oligosaccharides via a three-component coupling reaction

Karen Ka Yan Kung, Gai Li Li, Lan Zou, Hiu Chi Chong, Yun Chung Leung, Ka Hing Wong, Vanessa Kar Yan Lo, Chi Ming Che, Man Kin Wong

Research output: Journal article publicationJournal articleAcademic researchpeer-review

38 Citations (Scopus)


An efficient modular approach for single-site incorporation of two independent functionalities (amines and alkynes) into aldehyde-containing oligosaccharides concurrently by using a one-pot gold-mediated three-component coupling reaction in aqueous medium under mild conditions has been developed.
Original languageEnglish
Pages (from-to)925-930
Number of pages6
JournalOrganic and Biomolecular Chemistry
Issue number5
Publication statusPublished - 7 Feb 2012

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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