Gold-mediated bifunctional modification of oligosaccharides via a three-component coupling reaction

Karen Ka Yan Kung; Gai Li Li; Lan Zou; Hiu Chi Chong; Yun Chung Leung; Ka Hing Wong; Vanessa Kar Yan Lo; Chi Ming Che; Man Kin Wong

doi:10.1039/c1ob06429k

Gold-mediated bifunctional modification of oligosaccharides via a three-component coupling reaction

Karen Ka Yan Kung, Gai Li Li, Lan Zou, Hiu Chi Chong, Yun Chung Leung, Ka Hing Wong, Vanessa Kar Yan Lo, Chi Ming Che, Man Kin Wong

Research output: Journal article publication › Journal article › Academic research › peer-review

43 Citations (Scopus)

Abstract

An efficient modular approach for single-site incorporation of two independent functionalities (amines and alkynes) into aldehyde-containing oligosaccharides concurrently by using a one-pot gold-mediated three-component coupling reaction in aqueous medium under mild conditions has been developed.

Original language	English
Pages (from-to)	925-930
Number of pages	6
Journal	Organic and Biomolecular Chemistry
Volume	10
Issue number	5
DOIs	https://doi.org/10.1039/c1ob06429k
Publication status	Published - 7 Feb 2012

ASJC Scopus subject areas

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry

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10.1039/c1ob06429k

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title = "Gold-mediated bifunctional modification of oligosaccharides via a three-component coupling reaction",

abstract = "An efficient modular approach for single-site incorporation of two independent functionalities (amines and alkynes) into aldehyde-containing oligosaccharides concurrently by using a one-pot gold-mediated three-component coupling reaction in aqueous medium under mild conditions has been developed.",

author = "Kung, {Karen Ka Yan} and Li, {Gai Li} and Lan Zou and Chong, {Hiu Chi} and Leung, {Yun Chung} and Wong, {Ka Hing} and Lo, {Vanessa Kar Yan} and Che, {Chi Ming} and Wong, {Man Kin}",

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AU - Kung, Karen Ka Yan

AU - Li, Gai Li

AU - Zou, Lan

AU - Chong, Hiu Chi

AU - Leung, Yun Chung

AU - Wong, Ka Hing

AU - Lo, Vanessa Kar Yan

AU - Che, Chi Ming

AU - Wong, Man Kin

PY - 2012/2/7

Y1 - 2012/2/7

N2 - An efficient modular approach for single-site incorporation of two independent functionalities (amines and alkynes) into aldehyde-containing oligosaccharides concurrently by using a one-pot gold-mediated three-component coupling reaction in aqueous medium under mild conditions has been developed.

AB - An efficient modular approach for single-site incorporation of two independent functionalities (amines and alkynes) into aldehyde-containing oligosaccharides concurrently by using a one-pot gold-mediated three-component coupling reaction in aqueous medium under mild conditions has been developed.

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U2 - 10.1039/c1ob06429k

DO - 10.1039/c1ob06429k

M3 - Journal article

C2 - 22076205

SN - 1477-0520

VL - 10

SP - 925

EP - 930

JO - Organic and Biomolecular Chemistry

JF - Organic and Biomolecular Chemistry

IS - 5

ER -

Gold-mediated bifunctional modification of oligosaccharides via a three-component coupling reaction

Abstract

ASJC Scopus subject areas

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